Literature DB >> 8263017

Gp80 (clusterin; TRPM-2) mRNA level is enhanced in human renal clear cell carcinomas.

K Parczyk1, C Pilarsky, U Rachel, C Koch-Brandt.   

Abstract

The gp80 glycoprotein complex (clusterin, apolipoprotein J, TRPM-2) is a widely expressed protein that has been attributed functions in tissue remodelling, immune defense and transport of lipids and biologically active peptides. The expression of the protein appears to be elevated in several neurodegenerative, apoptotic and malignant processes. We show here that in patients with renal clear cell carcinoma gp80 mRNA is 3-fold overexpressed in tissue of the tumors compared with adjacent non-tumor tissue.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 8263017     DOI： 10.1007/bf01202200

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  17 in total

1.  Expression of a novel gene encoding a 51.5 kD precursor protein is induced by different retroviral oncogenes in quail neuroretinal cells.

Authors:  D Michel; G Gillet; M Volovitch; B Pessac; G Calothy; G Brun
Journal:  Oncogene Res       Date:  1989

2.  Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

Authors:  D E Jenne; J Tschopp
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

Review 3.  Clusterin: the intriguing guises of a widely expressed glycoprotein.

Authors:  D E Jenne; J Tschopp
Journal:  Trends Biochem Sci       Date:  1992-04       Impact factor: 13.807

4.  Proportions of mitotic and apoptotic cells in a range of untreated experimental tumours.

Authors:  C E Sarraf; I D Bowen
Journal:  Cell Tissue Kinet       Date:  1988-01

5.  Genomic sequencing.

Authors:  G M Church; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

6.  The making of strand-specific M13 probes.

Authors:  N Hu; J Messing
Journal:  Gene       Date:  1982-03       Impact factor: 3.688

7.  Induction of the TRPM-2 gene in cells undergoing programmed death.

Authors:  R Buttyan; C A Olsson; J Pintar; C Chang; M Bandyk; P Y Ng; I S Sawczuk
Journal:  Mol Cell Biol       Date:  1989-08       Impact factor: 4.272

8.  Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat.

Authors:  P C May; M Lampert-Etchells; S A Johnson; J Poirier; J N Masters; C E Finch
Journal:  Neuron       Date:  1990-12       Impact factor: 17.173

9.  Biosynthesis and molecular cloning of sulfated glycoprotein 2 secreted by rat Sertoli cells.

Authors:  M W Collard; M D Griswold
Journal:  Biochemistry       Date:  1987-06-16       Impact factor: 3.162

10.  Constitutive apical secretion of an 80-kD sulfated glycoprotein complex in the polarized epithelial Madin-Darby canine kidney cell line.

Authors:  J Urban; K Parczyk; A Leutz; M Kayne; C Kondor-Koch
Journal:  J Cell Biol       Date:  1987-12       Impact factor: 10.539
View more
  21 in total

1.  Overexpression of clusterin in human breast carcinoma.

Authors:  M Redondo; E Villar; J Torres-Muñoz; T Tellez; M Morell; C K Petito
Journal:  Am J Pathol       Date:  2000-08       Impact factor: 4.307

Review 2.  Targeting anti-apoptotic genes upregulated by androgen withdrawal using antisense oligonucleotides to enhance androgen- and chemo-sensitivity in prostate cancer.

Authors:  Martin E Gleave; Toby Zellweger; Kim Chi; Hideaki Miyake; Satoshi Kiyama; Laura July; Simon Leung
Journal:  Invest New Drugs       Date:  2002-05       Impact factor: 3.850

Review 3.  Androgens and prostate cancer.

Authors:  Alan I So; Antonio Hurtado-Coll; Martin E Gleave
Journal:  World J Urol       Date:  2003-10-29       Impact factor: 4.226

4.  Induction of clusterin by AKT--role in cytoprotection against docetaxel in prostate tumor cells.

Authors:  Bin Zhong; David A Sallman; Danielle L Gilvary; Daniele Pernazza; Eva Sahakian; Dillon Fritz; Jin Q Cheng; Ioannis Trougakos; Sheng Wei; Julie Y Djeu
Journal:  Mol Cancer Ther       Date:  2010-05-25       Impact factor: 6.261

Review 5.  Clusterin and chemoresistance.

Authors:  Julie Y Djeu; Sheng Wei
Journal:  Adv Cancer Res       Date:  2009       Impact factor: 6.242

6.  Loss of clusterin both in serum and tissue correlates with the tumorigenesis of esophageal squamous cell carcinoma via proteomics approaches.

Authors:  Li-Yong Zhang; Wan-Tao Ying; You-Sheng Mao; Hong-Zhi He; Yu Liu; Hui-Xin Wang; Fang Liu; Kun Wang; De-Chao Zhang; Ying Wang; Min Wu; Xiao-Hong Qian; Xiao-Hang Zhao
Journal:  World J Gastroenterol       Date:  2003-04       Impact factor: 5.742

Review 7.  Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer.

Authors:  Martin Gleave; Hideaki Miyake
Journal:  World J Urol       Date:  2005-01-26       Impact factor: 4.226

Review 8.  Mechanisms of the development of androgen independence in prostate cancer.

Authors:  Alan So; Martin Gleave; Antonio Hurtado-Col; Colleen Nelson
Journal:  World J Urol       Date:  2005-01-27       Impact factor: 4.226

9.  Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression.

Authors:  Dan Xie; Jonathan-S-T Sham; Wei-Fen Zeng; Li-Hong Che; Meng Zhang; Hui-Xi Wu; Han-Liang Lin; Jian-Ming Wen; Sze-Hang Lau; Liang Hu; Xin-Yuan Guan
Journal:  World J Gastroenterol       Date:  2005-06-07       Impact factor: 5.742

10.  Clusterin as a diagnostic and prognostic marker for transitional cell carcinoma of the bladder.

Authors:  Sahar M Hazzaa; Osama M Elashry; Ibtesam K Afifi
Journal:  Pathol Oncol Res       Date:  2009-09-09       Impact factor: 3.201
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.