Literature DB >> 8263003

Mechanisms of polymer degradation in implantable devices. 2. Poly(DL-lactic acid).

S A Ali1, P J Doherty, D F Williams.   

Abstract

The hydrolytic degradation of poly(DL-lactic acid) in an aqueous environment in which hydroxyl radicals have been generated has been investigated. Different methods (gel permeation chromatography, differential scanning calorimetry, and scanning electron microscopy) were employed to study the mechanisms of degradation of this amorphous physiologically absorbable polymer. The data indicated that the hydroxyl radical is likely to be a significant factor in the degradation of this polymer.

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Year:  1993        PMID： 8263003     DOI： 10.1002/jbm.820271108

Source DB:  PubMed          Journal:  J Biomed Mater Res        ISSN： 0021-9304


  13 in total

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