Literature DB >> 8262479

Relationship between the level of c-myc mRNA and histologic aggressiveness in thyroid tumors.

M I Romano1, M Grattone, M P Karner, S Moiguer, F Tetelbaum, L A Romano, E Illescas, R Padin, F Cueva, J A Burdman.   

Abstract

We investigated the relationship between the level of c-myc mRNA and histologic aggressiveness in thyroid tumors obtained at surgery. In thyroid carcinomas, there was a positive correlation between these two parameters, while in benign tumors there was no correlation between cellularity and the expression of the proto-oncogene c-myc. These results might be useful in the prognosis of thyroid tumors and consequently helpful in the management of the patient.

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Year:  1993        PMID: 8262479     DOI: 10.1159/000182718

Source DB:  PubMed          Journal:  Horm Res        ISSN: 0301-0163


  4 in total

Review 1.  The potential role of mTOR inhibitors in the treatment of endocrine tumors.

Authors:  S Grozinsky-Glasberg; I Shimon
Journal:  J Endocrinol Invest       Date:  2010-05-05       Impact factor: 4.256

2.  Potentiated anti-tumor effects of BETi by MEKi in anaplastic thyroid cancer.

Authors:  Xuguang Zhu; Sunmi Park; Woo Kyung Lee; Sheue-Yann Cheng
Journal:  Endocr Relat Cancer       Date:  2019-09       Impact factor: 5.678

3.  cMYC expression in thyroid follicular cell-derived carcinomas: a role in thyroid tumorigenesis.

Authors:  Hany I Sakr; Deborah J Chute; Christian Nasr; Charles D Sturgis
Journal:  Diagn Pathol       Date:  2017-10-03       Impact factor: 2.644

4.  Synergistic effects of BET and MEK inhibitors promote regression of anaplastic thyroid tumors.

Authors:  Xuguang Zhu; Erik Holmsen; Sunmi Park; Mark C Willingham; Jun Qi; Sheue-Yann Cheng
Journal:  Oncotarget       Date:  2018-10-23
  4 in total

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