Literature DB >> 8262204

mRNA amplification system by viral replicase in transgenic plants.

M Mori1, M Kaido, T Okuno, I Furusawa.   

Abstract

We have constructed transgenic tobacco plants (M1x2-FCP2IFN plants) expressing viral RNA replication genes of brome mosaic virus (BMV) and BMV RNA3 derivative (FCP2IFN) carrying the human gamma interferon (IFN-gamma) gene. In M1x2-FCP2IFN plants the RNA3 derivative expressed from the integrated cDNA was replicated and subgenomic RNA (i.e. mRNA of IFN-gamma) was produced by BMV replicase. The accumulation level of the mRNA of IFN-gamma was approximately 5-fold higher than that by the cauliflower mosaic virus (CaMV) 35S RNA promoter. In addition IFN-gamma accumulated in M1x2-FCP2IFN plants.

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Year:  1993        PMID： 8262204     DOI： 10.1016/0014-5793(93)81634-c

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

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Authors:  S M Angell; D C Baulcombe
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Review 2.  Genetic elements of plant viruses as tools for genetic engineering.

Authors:  A R Mushegian; R J Shepherd
Journal:  Microbiol Rev       Date:  1995-12

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Authors:  Masaki Nishikiori; Masashi Mori; Koji Dohi; Hideyasu Okamura; Etsuko Katoh; Satoshi Naito; Tetsuo Meshi; Masayuki Ishikawa
Journal:  PLoS Pathog       Date:  2011-12-08       Impact factor: 6.823

4.  Isolation of amaranthin synthetase from Chenopodium quinoa and construction of an amaranthin production system using suspension-cultured tobacco BY-2 cells.

Authors:  Tomohiro Imamura; Noriyoshi Isozumi; Yasuki Higashimura; Akio Miyazato; Hiroharu Mizukoshi; Shinya Ohki; Masashi Mori
Journal:  Plant Biotechnol J       Date:  2018-12-05       Impact factor: 9.803
  4 in total

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