Literature DB >> 8259079

Reduced inhibition of endothelial-derived relaxing factor causes the hyperdynamic circulation in chronic severe anemia.

I S Anand1, Y Chandrashekhar.   

Abstract

Patients with chronic severe anemia have a vasodilated state and hyperdynamic circulation. The cause of vasodilation in these patients is not known. We postulate that the low levels of hemoglobin in these patients results in reduced inhibition of basal EDRF activity leading to generalized vasodilation.

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Year:  1993        PMID: 8259079     DOI: 10.1016/0306-9877(93)90235-i

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  2 in total

1.  Acute normovolaemic anaemia prevents ethanol-induced gastric damage in rats through a blood flow related mechanism.

Authors:  M Casadevall; J M Piqué; I Cirera; M D Barrachina; J Terés
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1994-11       Impact factor: 3.000

2.  Sudden intraoperative pulmonary congestion in a patient with severe anemia transfused 3 days prior to surgery.

Authors:  Takeru Shimizu; Hiroshi Takahashi; Makoto Tanaka
Journal:  Saudi J Anaesth       Date:  2019 Jan-Mar
  2 in total

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