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Literature DB >> 8258991

Biology of monoclonal antibodies in tumor therapy.

Abstract

This paper gives an overview of the biology of monoclonal antibodies in tumor therapy. The complexity of the monoclonal antibody concept is discussed with functional aspects on tumor antigen, antigen binding, Ig isotypes and effector mechanisms involved.

Entities: Disease

Mesh：

Substances：
Antibodies, Monoclonal

Year: 1993 PMID： 8258991 DOI： 10.1007/bf02987764

Source DB: PubMed Journal: Med Oncol Tumor Pharmacother ISSN： 0736-0118

11 in total

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Journal: Nature Date: 1975-08-07 Impact factor: 49.962

2. Anti-idiotypic monoclonal antibody to a T-cell chronic lymphatic leukemia. Characterization of the antibody, in vitro effector functions and results of therapy.

Authors: C H Janson; M J Tehrani; H Mellstedt; H Wigzell
Journal: Cancer Immunol Immunother Date: 1989 Impact factor: 6.968

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Authors: G G Klaus; M B Pepys; K Kitajima; B A Askonas
Journal: Immunology Date: 1979-12 Impact factor: 7.397

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Authors: N K Jerne
Journal: Ann Immunol (Paris) Date: 1974-01

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Authors: G E Goodman; I Hellström; L Brodzinsky; C Nicaise; B Kulander; D Hummel; K E Hellström
Journal: J Clin Oncol Date: 1990-06 Impact factor: 44.544

6. Influence of antibody isotype on passive serotherapy of lymphoma.

Authors: E Y Denkers; C C Badger; J A Ledbetter; I D Bernstein
Journal: J Immunol Date: 1985-09 Impact factor: 5.422

7. Studies on B lymphoid tumors treated with monoclonal anti-idiotype antibodies: correlation with clinical responses.

Authors: J N Lowder; T C Meeker; M Campbell; C F Garcia; J Gralow; R A Miller; R Warnke; R Levy
Journal: Blood Date: 1987-01 Impact factor: 22.113

Review 8. Rational use of biological response modifiers in hematological malignancies--a review of treatment with interferon, cytotoxic cells and antibodies.

Authors: C H Janson; M Tehrani; H Wigzell; H Mellstedt
Journal: Leuk Res Date: 1989 Impact factor: 3.156