Literature DB >> 8258837

(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide.

L M Gaster1, A J Jennings, G F Joiner, F D King, K R Mulholland, S K Rahman, S Starr, P A Wyman, K A Wardle, E S Ellis.   

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Year:  1993        PMID： 8258837     DOI： 10.1021/jm00077a018

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

1.  Selective and functional 5-hydroxytryptamine4 receptor antagonism by SB 207266.

Authors:  K A Wardle; S Bingham; E S Ellis; L M Gaster; B Rushant; M I Smith; G J Sanger
Journal:  Br J Pharmacol       Date:  1996-06       Impact factor: 8.739

2.  An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors.

Authors:  Marcela Vettorazzi; Emilio Angelina; Santiago Lima; Tomas Gonec; Jan Otevrel; Pavlina Marvanova; Tereza Padrtova; Petr Mokry; Pavel Bobal; Lina M Acosta; Alirio Palma; Justo Cobo; Janette Bobalova; Jozef Csollei; Ivan Malik; Sergio Alvarez; Sarah Spiegel; Josef Jampilek; Ricardo D Enriz
Journal:  Eur J Med Chem       Date:  2017-08-10       Impact factor: 6.514

3.  Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomography.

Authors:  Rong Xu; Jinsoo Hong; Cheryl L Morse; Victor W Pike
Journal:  J Med Chem       Date:  2010-10-14       Impact factor: 7.446

4.  5-HT4 receptor antagonist affinities of SB207710, SB205008, and SB203186 in the human colon, rat oesophagus, and guinea-pig ileum peristaltic reflex.

Authors:  P G McLean; I M Coupar
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-08       Impact factor: 3.000

5.  The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon.

Authors:  K A Wardle; E S Ellis; G S Baxter; G A Kennett; L M Gaster; G J Sanger
Journal:  Br J Pharmacol       Date:  1994-07       Impact factor: 8.739

6.  Radioiodinated SB 207710 as a radioligand in vivo: imaging of brain 5-HT4 receptors with SPET.

Authors:  Victor W Pike; Christer Halldin; Kenji Nobuhara; Julka Hiltunen; Rachel S Mulligan; Carl-Gunnar Swahn; Per Karlsson; Hans Olsson; Susan P Hume; Ella Hirani; Jaqueline Whalley; Lyn S Pilowsky; Stig Larsson; Per-Olof Schnell; Peter J Ell; Lars Farde
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-09-23       Impact factor: 9.236
  6 in total

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