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Literature DB >> 8256235

Comparison of nebulised aerosol deposition in the lungs of healthy adults following oral and nasal inhalation.

Abstract

A standard jet nebuliser was used to generate a radiolabelled aerosol and the pattern of deposition within the airways of eight healthy adults was studied with a gamma camera. Penetration of aerosol to the lung was greatly reduced when breathing through the nose compared with mouth breathing.

Entities: Disease

Mesh：

Substances：

Year: 1993 PMID： 8256235 PMCID： PMC464831 DOI： 10.1136/thx.48.10.1045

Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.139

8 in total

1. Drug delivery from jet nebulisers.

Authors: M L Everard; A R Clark; A D Milner
Journal: Arch Dis Child Date: 1992-05 Impact factor: 3.791

2. Two methods of administering nebulized salbutamol: a controlled study.

Authors: D O Wood; D Chandler; A E Dugdale
Journal: Aust Paediatr J Date: 1978-09

3. Quantitative comparison of 99Tcm-aerosol and 81Krm ventilation images.

Authors: J E Agnew; R A Francis; D Pavia; S W Clarke
Journal: Clin Phys Physiol Meas Date: 1982-02

4. Facemask or mouthpiece for delivery of nebulized bronchodilator aerosols?

Authors: R D Steventon; R S Wilson
Journal: Br J Dis Chest Date: 1981-01

5. Response of asthmatic patients to fenoterol inhalation: a method of quantifying the airway bronchodilator dose.

Authors: R E Ruffin; M C Kenworthy; M T Newhouse
Journal: Clin Pharmacol Ther Date: 1978-03 Impact factor: 6.875

6. Deposition of carbenicillin aerosols in cystic fibrosis: effects of nebuliser system and breathing pattern.

Authors: S P Newman; G Woodman; S W Clarke
Journal: Thorax Date: 1988-04 Impact factor: 9.139

7. Delivery of albuterol and ipratropium bromide from two nebulizer systems in chronic stable asthma. Efficacy and pulmonary deposition.

Authors: M A Johnson; S P Newman; R Bloom; N Talaee; S W Clarke
Journal: Chest Date: 1989-07 Impact factor: 9.410

8. Droplet size distributions of nebulised aerosols for inhalation therapy.

Authors: S P Newman; P G Pellow; S W Clarke
Journal: Clin Phys Physiol Meas Date: 1986-05

8 in total

15 in total

Review 1. Ethical aspects of using radiolabelling in aerosol research.

Authors: M L Everard
Journal: Arch Dis Child Date: 2003-08 Impact factor: 3.791

Review 2. Nebuliser therapy in childhood.

Authors: P W Barry; C O'Callaghan
Journal: Thorax Date: 1997-04 Impact factor: 9.139

Comparison of nebulised aerosol deposition in the lungs of healthy adults following oral and nasal inhalation.

1. Drug delivery from jet nebulisers.

2. Two methods of administering nebulized salbutamol: a controlled study.

3. Quantitative comparison of 99Tcm-aerosol and 81Krm ventilation images.

4. Facemask or mouthpiece for delivery of nebulized bronchodilator aerosols?

5. Response of asthmatic patients to fenoterol inhalation: a method of quantifying the airway bronchodilator dose.

6. Deposition of carbenicillin aerosols in cystic fibrosis: effects of nebuliser system and breathing pattern.

7. Delivery of albuterol and ipratropium bromide from two nebulizer systems in chronic stable asthma. Efficacy and pulmonary deposition.

8. Droplet size distributions of nebulised aerosols for inhalation therapy.

Review 1. Ethical aspects of using radiolabelling in aerosol research.

Review 2. Nebuliser therapy in childhood.

3. Nebulised antibiotics for adults with cystic fibrosis.

Review 4. The science of nebulised drug delivery.

5. Development of an Inline Dry Powder Inhaler for Oral or Trans-Nasal Aerosol Administration to Children.

Review 6. Studies using radiolabelled aerosols in children.

7. Improvement of nebulised antibiotic delivery in cystic fibrosis.

8. Systemic availability and pharmacokinetics of nebulised budesonide in preschool children.

Review 9. Use of inhaler devices in pediatric asthma.

10. High-Efficiency Dry Powder Aerosol Delivery to Children: Review and Application of New Technologies.