Literature DB >> 8254678

Crystallization and X-ray diffraction study of recombinant platelet-derived endothelial cell growth factor.

G Spraggon1, D Stuart, C Ponting, C Finnis, D Sleep, Y Jones.   

Abstract

Crystals of recombinant platelet-derived endothelial cell growth factor (PD-ECGF) were obtained by the hanging drop vapour diffusion technique. The crystals belong to the space group P2(1)2(1)2(1) with unit cell dimensions a = 63.7 A, b = 70.4 A, c = 219.6, alpha = beta = gamma = 90 degrees, and probably contain a single dimer in the asymmetric unit. Diffraction to a minimum Bragg spacing of 3.5 A has been obtained using a synchrotron X-ray source.

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Year:  1993        PMID: 8254678     DOI: 10.1006/jmbi.1993.1632

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  3 in total

1.  Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implications for drug design.

Authors:  Kamel El Omari; Annelies Bronckaers; Sandra Liekens; Maria-Jésus Pérez-Pérez; Jan Balzarini; David K Stammers
Journal:  Biochem J       Date:  2006-10-15       Impact factor: 3.857

Review 2.  Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis.

Authors:  N S Brown; R Bicknell
Journal:  Biochem J       Date:  1998-08-15       Impact factor: 3.857

Review 3.  The dual role of thymidine phosphorylase in cancer development and chemotherapy.

Authors:  Annelies Bronckaers; Federico Gago; Jan Balzarini; Sandra Liekens
Journal:  Med Res Rev       Date:  2009-11       Impact factor: 12.944

  3 in total

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