Literature DB >> 825161

[Vitamin B12 metabolism of human granulocytes. Differences in vitamin B12 uptake of normal granulocytes and CML leukocytes].

R Pfeiffer.   

Abstract

The total cell B12 level in chronic myelocytic leukaemia (CML) is low. The uptake of 57Co-cyanocobalamin by normal granulocytes, lymphocytes and CML leukocytes was studied. It was found that the uptake of vitamin B12 was dependent on its concentration. The velocity of the uptake by CML leukocytes was decreased. The reaction showed a non-competitive inhibition. Lymphocytes had the lowest uptake. Na2EDTA inhibited the vitamin B12 uptake of normal granulocytes.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 825161     DOI： 10.1007/BF00995222

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  12 in total

1.  SEPARATION OF LYMPHOCYTES, POLYMORPHONUCLEAR LEUKOCYTES AND MONOCYTES ON GLASS COLUMNS, INCLUDING TISSUE CULTURE OBSERVATIONS.

Authors:  Y RABINOWITZ
Journal:  Blood       Date:  1964-06       Impact factor: 22.113

2.  Clearance of intravenously injected radioactive cobalt-labeled vitamin B12 in chronic myeloid leukemia and other conditions.

Authors:  N D RITZ; L M MEYER
Journal:  Cancer       Date:  1960 Sep-Oct       Impact factor: 6.860

3.  The level of vitamin B12 in circulating leukaemic leucocytes.

Authors:  H M KIDD; J W THOMAS
Journal:  Br J Haematol       Date:  1962-01       Impact factor: 6.998

4.  The plasma clearance and urinary excretion of parenterally administered 58Co B12.

Authors:  D L MOLLIN; W R PITNEY; S J BAKER; J E BRADLEY
Journal:  Blood       Date:  1956-01       Impact factor: 22.113

5.  Co60 vitamin B12 binding capacity of human leukocytes.

Authors:  L M MEYER; E P CRONKITE; I F MILLER; C W MULZAC; I JONES
Journal:  Blood       Date:  1962-02       Impact factor: 22.113

6.  Uptake of vitamin B 12 by phytohaemagglutinin-transformed lymphocytes.

Authors:  A V Hoffbrand; E Tripp; K C Das
Journal:  Br J Haematol       Date:  1973-02       Impact factor: 6.998

7.  A vitamin B12 binder with transcobalmin I characteristics synthesized and released by human granulocytes in vitro.

Authors:  B Rachmilewitz; M Rachmilewitz; J Gross
Journal:  Br J Haematol       Date:  1974-04       Impact factor: 6.998

8.  Correation between vario blood white cell pools and the serum B12-binding capaities.

Authors:  G Chikkappa; J Corcino; M L Greenerg; V Herert
Journal:  Blood       Date:  1971-02       Impact factor: 22.113

9.  Granulocyte release of vitamin B12-binders in vivo and in vitro in leukaemia and non-neoplastic leucocytosis.

Authors:  R Gullberg; P Riezenstein
Journal:  Scand J Haematol       Date:  1975-12

10.  Vitamin B12-binding proteins of r-type, cobalophilin.

Authors:  U H Stenman
Journal:  Scand J Haematol       Date:  1975-04
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.