Literature DB >> 8250863

A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39.

P Storici1, M Zanetti.   

Abstract

We have recently shown that a group of antimicrobial peptides of bovine neutrophils share highly identical pro-sequences. In this paper we report the cDNA sequence of a 172 amino acid residue pig myeloid protein showing a similar pro-sequence of 101 residues. The carboxyl-moiety of the predicted protein is identical to the mature form of the proline- and arginine-rich antibacterial peptide named PR-39, isolated from pig intestine.

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Year:  1993        PMID： 8250863     DOI： 10.1006/bbrc.1993.2358

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  14 in total

1.  Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide.

Authors:  Y Gao; S Lecker; M J Post; A J Hietaranta; J Li; R Volk; M Li; K Sato; A K Saluja; M L Steer; A L Goldberg; M Simons
Journal:  J Clin Invest       Date:  2000-08       Impact factor: 14.808

Review 2.  Mammalian antibiotic peptides.

Authors:  P Síma; I Trebichavský; K Sigler
Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.099

3.  Regulation of cathelicidin gene expression: induction by lipopolysaccharide, interleukin-6, retinoic acid, and Salmonella enterica serovar typhimurium infection.

Authors:  H Wu; G Zhang; J E Minton; C R Ross; F Blecha
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

4.  FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.

Authors:  B Agerberth; H Gunne; J Odeberg; P Kogner; H G Boman; G H Gudmundsson
Journal:  Proc Natl Acad Sci U S A       Date:  1995-01-03       Impact factor: 11.205

5.  Antimicrobial peptides in the gastrointestinal tract.

Authors:  Y R Mahida; F Rose; W C Chan
Journal:  Gut       Date:  1997-02       Impact factor: 23.059

6.  Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds.

Authors:  R L Gallo; M Ono; T Povsic; C Page; E Eriksson; M Klagsbrun; M Bernfield
Journal:  Proc Natl Acad Sci U S A       Date:  1994-11-08       Impact factor: 11.205

7.  Salmonella infection increases porcine antibacterial peptide concentrations in serum.

Authors:  G Zhang; C R Ross; S S Dritz; J C Nietfeld; F Blecha
Journal:  Clin Diagn Lab Immunol       Date:  1997-11

8.  Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity.

Authors:  Z Oren; J C Lerman; G H Gudmundsson; B Agerberth; Y Shai
Journal:  Biochem J       Date:  1999-08-01       Impact factor: 3.857

9.  Constitutive expression of antimicrobial peptide PR-39 in transgenic mice significantly enhances resistance to bacterial infection and promotes growth.

Authors:  Fang Zeng; Rui Dong; Chengcheng Zhao; Dewu Liu; Enqin Zheng; Changxu Song; Zhenfang Wu; Zicong Li
Journal:  Transgenic Res       Date:  2018-07-12       Impact factor: 2.788

10.  Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39.

Authors:  G H Gudmundsson; K P Magnusson; B P Chowdhary; M Johansson; L Andersson; H G Boman
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-18       Impact factor: 11.205
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