| Literature DB >> 8250014 |
A Suzuki1, T Takahashi, Y Okuno, R Tsuyuoka, Y Sasaki, M Fukumoto, H Katakami, K Kita, T Shibuya.
Abstract
We examined whether or not parathyroid hormone-related protein (PTH-rP) is produced in cultured human myeloma cells. PTH-rP protein was detected in the cell extract of one (U266) of 6 myeloma cell lines examined by radioimmunoassay. Also we demonstrated the expression of PTH-rP mRNA in all of the 6 lines. These findings indicate that PTH-rP may be one of the factors responsible for the bone destruction or hypercalcemia in multiple myeloma.Entities:
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Year: 1994 PMID： 8250014 DOI： 10.1002/ajh.2830450115
Source DB: PubMed Journal: Am J Hematol ISSN： 0361-8609 Impact factor: 10.047