Literature DB >> 8249433

Mucosal immunization with a subunit respiratory syncytial virus vaccine in mice.

E E Walsh1.   

Abstract

The protective efficacy of mucosal immunization with purified respiratory syncytial virus (RSV) fusion protein (F) using cholera toxin (CT) as an adjuvant was assessed in mice. Intranasal vaccination with F+CT induced F-specific serum IgG and nasal IgA and resulted in 75% protection from nasal virus replication compared with control mice. Intranasal CT+F with simultaneous parenteral F provided complete protection equivalent to intranasal live virus immunization.

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Year:  1993        PMID： 8249433     DOI： 10.1016/0264-410x(93)90075-9

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  7 in total

1.  Mucosally induced immunoglobulin E-associated inflammation in the respiratory tract.

Authors:  J W Simecka; R J Jackson; H Kiyono; J R McGhee
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

2.  Targeting of nasal mucosa-associated antigen-presenting cells in vivo with an outer membrane protein A derived from Klebsiella pneumoniae.

Authors:  L Goetsch; A Gonzalez; H Plotnicky-Gilquin; J F Haeuw; J P Aubry; A Beck; J Y Bonnefoy; N Corvaïa
Journal:  Infect Immun       Date:  2001-10       Impact factor: 3.441

3.  Immunoglobulin A (IgA) responses and IgE-associated inflammation along the respiratory tract after mucosal but not systemic immunization.

Authors:  L M Hodge; M Marinaro; H P Jones; J R McGhee; H Kiyono; J W Simecka
Journal:  Infect Immun       Date:  2001-04       Impact factor: 3.441

4.  Development of antibody-secreting cells and antigen-specific T cells in cervical lymph nodes after intranasal immunization.

Authors:  H Y Wu; E B Nikolova; K W Beagley; J H Eldridge; M W Russell
Journal:  Infect Immun       Date:  1997-01       Impact factor: 3.441

5.  Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats.

Authors:  Hoyin Mok; Sujin Lee; Thomas J Utley; Bryan E Shepherd; Vasiliy V Polosukhin; Martha L Collier; Nancy L Davis; Robert E Johnston; James E Crowe
Journal:  J Virol       Date:  2007-10-10       Impact factor: 5.103

6.  Immunogenicity and efficacy of recombinant RSV-F vaccine in a mouse model.

Authors:  Shree R Singh; Vida A Dennis; Christina L Carter; Shreekumar R Pillai; Ayanna Jefferson; Shivendra V Sahi; Eddie G Moore
Journal:  Vaccine       Date:  2007-06-26       Impact factor: 3.641

Review 7.  Cholera toxin: a paradigm of a multifunctional protein.

Authors:  Kaushik Bharati; Nirmal K Ganguly
Journal:  Indian J Med Res       Date:  2011-02       Impact factor: 2.375
  7 in total

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