| Literature DB >> 8249082 |
K R Trenholme1, D E Kum, A K Raiko, N Gibson, A Narara, M P Alpers.
Abstract
The sensitivity of Plasmodium falciparum to amodiaquine was assessed in children in the Madang region of Papua New Guinea. Fifty-four tests in vivo were carried out and 19 (35%) of these showed resistance at the RII or RIII level. Twenty-two of the 43 isolates tested showed some degree of resistance to amodiaquine in vitro. A negative correlation between the age of the patient and apparent resistance of the parasite in vivo was observed. There was no correlation between resistance in vivo and in vitro.Entities:
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Year: 1993 PMID： 8249082 DOI： 10.1016/0035-9203(93)90038-r
Source DB: PubMed Journal: Trans R Soc Trop Med Hyg ISSN： 0035-9203 Impact factor: 2.184