Literature DB >> 8248124

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.

E Lai1, K L Clark, S K Burley, J E Darnell.   

Abstract

A family of transcription factors, first identified as hepatocyte nuclear factors (HNF-3 alpha, -3 beta, and -3 gamma) and as a homeotic Drosophila mutant, fork head, has been intensively studied for the past 4 years. Important findings have emerged about the structure of the DNA-binding portion of the proteins as well as biologic discoveries about the diversity of the family and its implied role in early development.

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Year:  1993        PMID： 8248124      PMCID： PMC47788          DOI： 10.1073/pnas.90.22.10421

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  The Drosophila sloppy paired locus encodes two proteins involved in segmentation that show homology to mammalian transcription factors.

Authors:  U Grossniklaus; R K Pearson; W J Gehring
Journal:  Genes Dev       Date:  1992-06       Impact factor: 11.361

2.  The fork head domain: a novel DNA binding motif of eukaryotic transcription factors?

Authors:  D Weigel; H Jäckle
Journal:  Cell       Date:  1990-11-02       Impact factor: 41.582

3.  HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally.

Authors:  E Lai; V R Prezioso; E Smith; O Litvin; R H Costa; J E Darnell
Journal:  Genes Dev       Date:  1990-08       Impact factor: 11.361

4.  Characterization and chromosomal mapping of the gene encoding the cellular DNA binding protein HTLF.

Authors:  C Li; A J Lusis; R Sparkes; S M Tran; R Gaynor
Journal:  Genomics       Date:  1992-07       Impact factor: 5.736

5.  The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo.

Authors:  D Weigel; G Jürgens; F Küttner; E Seifert; H Jäckle
Journal:  Cell       Date:  1989-05-19       Impact factor: 41.582

6.  Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

Authors:  E Lai; V R Prezioso; W F Tao; W S Chen; J E Darnell
Journal:  Genes Dev       Date:  1991-03       Impact factor: 11.361

7.  A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain.

Authors:  M L Dirksen; M Jamrich
Journal:  Genes Dev       Date:  1992-04       Impact factor: 11.361

8.  Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain.

Authors:  W Tao; E Lai
Journal:  Neuron       Date:  1992-05       Impact factor: 17.173

9.  Cloning of a cellular factor, interleukin binding factor, that binds to NFAT-like motifs in the human immunodeficiency virus long terminal repeat.

Authors:  C Li; C F Lai; D S Sigman; R B Gaynor
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-01       Impact factor: 11.205

10.  Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.

Authors:  H Sasaki; B L Hogan
Journal:  Development       Date:  1993-05       Impact factor: 6.868
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  74 in total

1.  The structural basis of acyl coenzyme A-dependent regulation of the transcription factor FadR.

Authors:  D M van Aalten; C C DiRusso; J Knudsen
Journal:  EMBO J       Date:  2001-04-17       Impact factor: 11.598

2.  Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR.

Authors:  J Nakae; V Barr; D Accili
Journal:  EMBO J       Date:  2000-03-01       Impact factor: 11.598

3.  Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF.

Authors:  D J Garry; A Meeson; J Elterman; Y Zhao; P Yang; R Bassel-Duby; R S Williams
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-09       Impact factor: 11.205

4.  Mechanisms controlling differential promoter-occupancy by the yeast forkhead proteins Fkh1p and Fkh2p: implications for regulating the cell cycle and differentiation.

Authors:  P C Hollenhorst; G Pietz; C A Fox
Journal:  Genes Dev       Date:  2001-09-15       Impact factor: 11.361

5.  Transient expression of a winged-helix protein, MNF-beta, during myogenesis.

Authors:  Q Yang; R Bassel-Duby; R S Williams
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

6.  Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer.

Authors:  Pang-Kuo Lo; Ji Shin Lee; Xiaohui Liang; Liangfeng Han; Tsuyoshi Mori; Mary Jo Fackler; Helen Sadik; Pedram Argani; Tej K Pandita; Saraswati Sukumar
Journal:  Cancer Res       Date:  2010-06-29       Impact factor: 12.701

7.  Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder.

Authors:  Przemyslaw Szafranski; Avinash V Dharmadhikari; Erwin Brosens; Priyatansh Gurha; Katarzyna E Kolodziejska; Ou Zhishuo; Piotr Dittwald; Tadeusz Majewski; K Naga Mohan; Bo Chen; Richard E Person; Dick Tibboel; Annelies de Klein; Jason Pinner; Maya Chopra; Girvan Malcolm; Gregory Peters; Susan Arbuckle; Sixto F Guiang; Virginia A Hustead; Jose Jessurun; Russel Hirsch; David P Witte; Isabelle Maystadt; Neil Sebire; Richard Fisher; Claire Langston; Partha Sen; Paweł Stankiewicz
Journal:  Genome Res       Date:  2012-10-03       Impact factor: 9.043

8.  Mechanisms of inhibition of nuclear hormone receptor-dependent hepatitis B virus replication by hepatocyte nuclear factor 3beta.

Authors:  Hong Tang; Alan McLachlan
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

9.  An array of binding sites for hepatocyte nuclear factor 4 of high and low affinities modulates the liver-specific enhancer for the human alpha1-microglobulin/bikunin precursor.

Authors:  P Rouet; G Raguenez; P Ruminy; J P Salier
Journal:  Biochem J       Date:  1998-09-15       Impact factor: 3.857

10.  Isolation and expression analysis of foxj1 and foxj1.2 in zebrafish embryos.

Authors:  Emil Aamar; Igor B Dawid
Journal:  Int J Dev Biol       Date:  2008       Impact factor: 2.203
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