Literature DB >> 8244889

Stereostructure and NMR characterization of the antibiotic candidin.

J Pawlak1, P Sowiński, E Borowski, P Gariboldi.   

Abstract

The stereostructure of the heptaene macrolide antibiotic candidin was established on the basis of NMR studies: 13C, DQF-COSY, ROESY and C,H-COSY experiments. The absolute configuration of the candidin chiral centers were assigned as 3R, 5S, 10R, 11R, 13R, 15S, 16R, 17S, 19S, 34S, 35R, 36R and 37S.

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Year:  1993        PMID: 8244889     DOI: 10.7164/antibiotics.46.1598

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  5 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

2.  The stereostructure of candicidin D.

Authors:  Katarzyna Szwarc; Paweł Szczeblewski; Paweł Sowiński; Edward Borowski; Jan Pawlak
Journal:  J Antibiot (Tokyo)       Date:  2015-02-25       Impact factor: 2.649

3.  (+)-Rimocidin synthetic studies: construction of the C(1-27) aglycone skeleton.

Authors:  Amos B Smith; Megan A Foley; Shuzhi Dong; Alia Orbin
Journal:  J Org Chem       Date:  2009-08-21       Impact factor: 4.354

4.  A unified approach to polyene macrolides: synthesis of candidin and nystatin polyols.

Authors:  Isao Kadota; Yueqing Hu; Garrick K Packard; Scott D Rychnovsky
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-10       Impact factor: 11.205

Review 5.  New Glycosylated Polyene Macrolides: Refining the Ore from Genome Mining.

Authors:  Patrick Caffrey; Mark Hogan; Yuhao Song
Journal:  Antibiotics (Basel)       Date:  2022-03-03
  5 in total

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