Literature DB >> 824395

Effect of thyroid status on the thyrotrophin-releasing hormone-degrading activity of rat serum.

N White, S L Jeffcoate, E C Griffiths, K C Hooper.   

Abstract

The TRH-degrading activity of rat serum in vitro is five times more potent than that of human serum. In rats, it is significantly reduced in hypothyroidism (thiouracil-induced) and significantly increased in hyperthyroidism (T3 or T4-induced). This suggests a possible role in the regulation of adenohypophysial-thyroid function which is probably, in turn, dependent on thyroid hormone, rather than TSH, levels.

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Year:  1976        PMID： 824395     DOI： 10.1677/joe.0.0710013

Source DB:  PubMed          Journal:  J Endocrinol        ISSN： 0022-0795            Impact factor:   4.286


  4 in total

1.  Actions of alpha-, beta- and ganglion-blockade on the pressor responses to angiotensins I and II in the conscious rabbit [proceedings].

Authors:  K A Munday; A R Noble; B P Rowe
Journal:  J Physiol       Date:  1978-02       Impact factor: 5.182

2.  Lower levels of thyrotropin-releasing hormone-degrading activity in human cord and in maternal sera than in the serum of euthyroid, nonpregnant adults.

Authors:  J T Neary; C Nakamura; I J Davies; M Soodak; F Maloof
Journal:  J Clin Invest       Date:  1978-07       Impact factor: 14.808

3.  The physiological role of thyrotropin-releasing hormone in the regulation of thyroid-stimulating hormone and prolactin secretion in the rat.

Authors:  A R Harris; D Christianson; M S Smith; S L Fang; L E Braverman; A G Vagenakis
Journal:  J Clin Invest       Date:  1978-02       Impact factor: 14.808

4.  Effect of unilateral or bilateral thyroidectomy on TRH content of hypothalamus halves.

Authors:  I Gerendai; A Nemeskéri; A Faivre-Bauman; D Grouselle; A Tixier-Vidal
Journal:  J Endocrinol Invest       Date:  1985-08       Impact factor: 4.256
  4 in total

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