Literature DB >> 824267

Pleiotropic, extragenic suppression of dna mutants in Bacillus subtilis.

A G Siccardi, S Ottolenghi, A Fortunato, G Mazza.   

Abstract

Thermosensitive (dna) mutants of Bacillus subtilis defective in deoxyribonucleic acid replication can be divided into two groups on the basis of their ability to spontaneously yield secondary mutants with an HDS phenotype (thermoin-sensitivity and resistance to aryl-azo-pyrimidines) at frequencies higher than 10(-8). Such a phenotype is due to alleles at the hds locus (mapping close to cysA), which act as extragenic pleiotropic suppressors. HDS suppressibility has been used as a screening tool to identify new dna strains among uncharacterized temperature-sensitive mutants.

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Year:  1976        PMID： 824267      PMCID： PMC232841          DOI： 10.1128/jb.128.1.174-181.1976

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  24 in total

1.  TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE.

Authors:  J Spizizen
Journal:  Proc Natl Acad Sci U S A       Date:  1958-10-15       Impact factor: 11.205

2.  Osmotic reversal of temperature sensitivity in Escherichia coli.

Authors:  A Z Bilsky; J B Armstrong
Journal:  J Bacteriol       Date:  1973-01       Impact factor: 3.490

3.  Asymmetric bidirectional replication of Bacillus subtilis chromosome.

Authors:  H Hara; H Yoshikawa
Journal:  Nat New Biol       Date:  1973-08-15

4.  Mutagenic DNA polymerase in B. subtilis.

Authors:  G W Bazill; J D Gross
Journal:  Nat New Biol       Date:  1973-06-20

5.  Temperature-sensitive DNA synthesis mutants of Bacillus subtilis--appendix: theory of density transfer for symmetric chromosome replication.

Authors:  K White; N Sueoka
Journal:  Genetics       Date:  1973-02       Impact factor: 4.562

6.  [Effects of salts on the process of cell division in E. coli].

Authors:  M Ricard; Y Hirota
Journal:  C R Acad Hebd Seances Acad Sci D       Date:  1969-03-03

7.  Crystal structure of an inhibitor and a model for inhibition of replicative DNA synthesis.

Authors:  C L Coulter; N R Cozzarelli
Journal:  J Mol Biol       Date:  1975-01-25       Impact factor: 5.469

8.  Effect of 6-(p-hydroxyphenyl)-azouracil on B. subtilis DNA polymerases.

Authors:  G W Bazill; J D Gross
Journal:  Nat New Biol       Date:  1972-11-15

9.  Effect of caffeine on the recombination process of Bacillus subtilis.

Authors:  G Mazza; H M Eisenstark; M C Serra; M Polsinelli
Journal:  Mol Gen Genet       Date:  1972

10.  Hydroxyphenylazopyrimidines: characterization of the active forms and their inhibitory action on a DNA polymerase from Bacillus subtilis.

Authors:  J M Mackenzie; M M Neville; G E Wright; N C Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1973-02       Impact factor: 11.205
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  3 in total

1.  Genetic analysis of a class of polymyxin resistant partial revertants of stage O sporulation mutants of Bacillus subtilis: map of the chromosome region near the origin of replication.

Authors:  J Trowsdale; S M Chen; J A Hoch
Journal:  Mol Gen Genet       Date:  1979-05-23

Review 2.  Revised genetic linkage map of Bacillus subtilis.

Authors:  P J Piggot; J A Hoch
Journal:  Microbiol Rev       Date:  1985-06

Review 3.  The Bacillus subtilis chromosome.

Authors:  D J Henner; J A Hoch
Journal:  Microbiol Rev       Date:  1980-03
  3 in total

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