Literature DB >> 8242068

The density of transcriptional elements in promoter and non-promoter sequences.

D S Prestridge1, C Burks.   

Abstract

Using data currently available from transcriptional element (TE) databases, we have analyzed the density of these elements in both promoter and non-promoter sequences obtained from the GenBank sequence database. The density of putative TEs in non-promoter sequences was about 16% higher than that seen in pseudo-random DNA sequences. Promoter TE density from the transcription startsite to 100 basepairs upstream was found to be about 42% higher than in non-promoter sequences. However, the extensive overlap of putative TE densities between promoters and non-promoters confounds an attempt to use TE density as a simple discriminator.

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Year:  1993        PMID： 8242068     DOI： 10.1093/hmg/2.9.1449

Source DB:  PubMed          Journal:  Hum Mol Genet        ISSN： 0964-6906            Impact factor:   6.150


  6 in total

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5.  Features of mammalian microRNA promoters emerge from polymerase II chromatin immunoprecipitation data.

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  6 in total

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