Literature DB >> 8241270

Structure of the human progesterone receptor gene.

M Misrahi1, P Y Venencie, P Saugier-Veber, S Sar, P Dessen, E Milgrom.   

Abstract

The complete organization of the human progesterone receptor (hPR) gene has been determined. It spans over 90 kbp and contains eight exons. The first exon encodes the N-terminal part of the receptor. The DNA binding domain is encoded by two exons, each exon corresponding to one zinc finger. The steroid binding domain is encoded by five exons. The nucleotide sequence of 1144 bp of the 5' flanking region has been determined.

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Year:  1993        PMID: 8241270     DOI: 10.1016/0167-4781(93)90156-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  14 in total

1.  Reverse transcription-polymerase chain reaction (RT-PCR) assays of estrogen and progesterone receptors in breast cancer.

Authors:  S Chevillard; A Müller; C Levalois; C Lainé-Bidron; P Vielh; H Magdelénat
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

2.  Genetic variation in the progesterone receptor gene and ovarian cancer risk.

Authors:  Kathryn L Terry; Immaculata De Vivo; Linda Titus-Ernstoff; Patrick M Sluss; Daniel W Cramer
Journal:  Am J Epidemiol       Date:  2005-03-01       Impact factor: 4.897

3.  Identification of single-nucleotide polymorphism in the progesterone receptor gene and its association with reproductive traits in rabbits.

Authors:  R Peiró; M Merchán; M A Santacreu; M J Argente; M L García; J M Folch; A Blasco
Journal:  Genetics       Date:  2008-09-14       Impact factor: 4.562

4.  Detection of progesterone receptor forms A and B by immunohistochemical analysis.

Authors:  P A Mote; J F Johnston; T Manninen; P Tuohimaa; C L Clarke
Journal:  J Clin Pathol       Date:  2001-08       Impact factor: 3.411

Review 5.  The loss of estrogen and progesterone receptor gene expression in human breast cancer.

Authors:  R G Lapidus; S J Nass; N E Davidson
Journal:  J Mammary Gland Biol Neoplasia       Date:  1998-01       Impact factor: 2.673

6.  Identification of novel transcript variants of estrogen receptor α, β and progesterone receptor gene in human endometrium.

Authors:  Anette Springwald; Claus Lattrich; Maciek Skrzypczak; Regina Goerse; Olaf Ortmann; Oliver Treeck
Journal:  Endocrine       Date:  2010-03-25       Impact factor: 3.633

Review 7.  The role of glucocorticoids and progestins in inflammatory, autoimmune, and infectious disease.

Authors:  A Sasha Tait; Cherie L Butts; Esther M Sternberg
Journal:  J Leukoc Biol       Date:  2008-07-29       Impact factor: 4.962

8.  Inhibiting gene expression with locked nucleic acids (LNAs) that target chromosomal DNA.

Authors:  Randall L Beane; Rosalyn Ram; Sylvie Gabillet; Khalil Arar; Brett P Monia; David R Corey
Journal:  Biochemistry       Date:  2007-05-31       Impact factor: 3.162

9.  Inhibiting gene expression with peptide nucleic acid (PNA)--peptide conjugates that target chromosomal DNA.

Authors:  Jiaxin Hu; David R Corey
Journal:  Biochemistry       Date:  2007-05-31       Impact factor: 3.162

10.  Role of progesterone receptor polymorphisms in the recurrent spontaneous abortions: Indian case.

Authors:  Meka Aruna; Theeya Nagaraja; Sadaranga Andal; Surapaneni Tarakeswari; Pisapati V S Sirisha; Alla G Reddy; Kumarasamy Thangaraj; Lalji Singh; B Mohan Reddy
Journal:  PLoS One       Date:  2010-01-14       Impact factor: 3.240

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