Literature DB >> 8240427

"Chronic Lyme disease" as the incorrect diagnosis in patients with fibromyalgia.

V M Hsu1, S J Patella, L H Sigal.   

Abstract

OBJECTIVE: To evaluate a large number of patients referred with persistent symptoms thought to represent chronic Lyme disease.
METHODS: We retrospectively reviewed the charts of nearly 800 patients referred with persisting nonspecific musculoskeletal and/or neurologic symptoms thought to represent chronic Lyme disease.
RESULTS: Seventy-seven patients were found to have fibromyalgia, not ongoing Lyme disease, as the explanation of their chronic symptoms. Many had received multiple courses of antibiotic therapy for symptoms of fibromyalgia mistakenly attributed to chronic Lyme disease. No patient reported permanent and/or total resolution of fibromyalgia symptoms following antibiotic therapy. Appropriate therapy for fibromyalgia in those who remained compliant, however, was often effective in improving some if not all of the chronic symptoms.
CONCLUSION: Fibromyalgia is a treatable and potentially curable disorder, and should be considered in the evaluation of patients with "refractory Lyme disease."

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Year:  1993        PMID: 8240427     DOI: 10.1002/art.1780361103

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  13 in total

1.  Psychiatric comorbidity and other psychological factors in patients with "chronic Lyme disease".

Authors:  Afton L Hassett; Diane C Radvanski; Steven Buyske; Shantal V Savage; Leonard H Sigal
Journal:  Am J Med       Date:  2009-09       Impact factor: 4.965

Review 2.  A systematic review of Borrelia burgdorferi morphologic variants does not support a role in chronic Lyme disease.

Authors:  Paul M Lantos; Paul G Auwaerter; Gary P Wormser
Journal:  Clin Infect Dis       Date:  2013-12-12       Impact factor: 9.079

3.  2012 Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: executive summary.

Authors:  Mary-Ann Fitzcharles; Peter A Ste-Marie; Don L Goldenberg; John X Pereira; Susan Abbey; Manon Choinière; Gordon Ko; Dwight E Moulin; Pantelis Panopalis; Johanne Proulx; Yoram Shir
Journal:  Pain Res Manag       Date:  2013 May-Jun       Impact factor: 3.037

4.  Correlation of seroreactivity with response to antibiotics in pediatric Lyme borreliosis.

Authors:  P T Fawcett; C D Rosé; K M Gibney; R A Doughty
Journal:  Clin Diagn Lab Immunol       Date:  1997-01

5.  Implications of gender in chronic Lyme disease.

Authors:  Gary P Wormser; Eugene D Shapiro
Journal:  J Womens Health (Larchmt)       Date:  2009-06       Impact factor: 2.681

Review 6.  Fibromyalgia: an update and immunological aspects.

Authors:  Eduardo S Paiva; Evelin Diana Goldenberg Mariano da Costa; Morton Scheinberg
Journal:  Curr Pain Headache Rep       Date:  2008-10

Review 7.  Fibromyalgia, hepatitis C infection, and the cytokine connection.

Authors:  Mollie E Thompson; André Barkhuizen
Journal:  Curr Pain Headache Rep       Date:  2003-10

8.  Differential diagnoses of suspected Lyme borreliosis or post-Lyme-disease syndrome.

Authors:  M F Seidel; A Belda Domene; H Vetter
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2007-09       Impact factor: 3.267

9.  Fibromyalgia syndrome: etiology, pathogenesis, diagnosis, and treatment.

Authors:  Enrico Bellato; Eleonora Marini; Filippo Castoldi; Nicola Barbasetti; Lorenzo Mattei; Davide Edoardo Bonasia; Davide Blonna
Journal:  Pain Res Treat       Date:  2012-11-04

Review 10.  Rheumatic mimics and selected triggers of fibromyalgia.

Authors:  Katja F Daoud; Andre Barkhuizen
Journal:  Curr Pain Headache Rep       Date:  2002-08
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