Literature DB >> 8234437

A comparison of Agiolax and lactulose in elderly patients with chronic constipation.

A P Passmore1, K W Davies, P G Flanagan, C Stoker, M G Scott.   

Abstract

In a double-blind crossover study the efficacies of Agiolax, a combination of fibre and senna pod, and lactulose were compared in 77 long-stay elderly patients with chronic constipation. Mean daily bowel frequency, stool consistency and ease of evacuation were significantly greater with Agiolax than lactulose. The recommended dose was exceeded more frequently with lactulose than Agiolax (chi 2 = 8.38, p < 0.01). Adverse effects were not different for the 2 treatments. In long-stay elderly patients with chronic constipation Agiolax and lactulose were well tolerated, but Agiolax proved a more effective treatment.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8234437     DOI： 10.1159/000139865

Source DB:  PubMed          Journal:  Pharmacology        ISSN： 0031-7012            Impact factor:   2.547


  12 in total

1.  Effectiveness of laxatives in adults.

Authors:  M Petticrew; M Rodgers; A Booth
Journal:  Qual Health Care       Date:  2001-12

2.  Lack of objective evidence of efficacy of laxatives in chronic constipation.

Authors:  Michael P Jones; Nicholas J Talley; Guy Nuyts; Dominique Dubois
Journal:  Dig Dis Sci       Date:  2002-10       Impact factor: 3.199

Review 3.  Management of chronic constipation in patients with diabetes mellitus.

Authors:  V G M Prasad; Philip Abraham
Journal:  Indian J Gastroenterol       Date:  2016-12-17

Review 4.  What's the 'best buy' for treatment of constipation? Results of a systematic review of the efficacy and comparative efficacy of laxatives in the elderly.

Authors:  M Petticrew; I Watt; M Brand
Journal:  Br J Gen Pract       Date:  1999-05       Impact factor: 5.386

5.  Systematic Review: FDA-Approved Prescription Medications for Adults With Constipation.

Authors:  Brooks D Cash; Brian E Lacy
Journal:  Gastroenterol Hepatol (N Y)       Date:  2006-10

Review 6.  Update on the management of constipation in the elderly: new treatment options.

Authors:  Satish S C Rao; Jorge T Go
Journal:  Clin Interv Aging       Date:  2010-08-09       Impact factor: 4.458

7.  Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation (part II: treatment).

Authors:  Antonio Bove; Massimo Bellini; Edda Battaglia; Renato Bocchini; Dario Gambaccini; Vincenzo Bove; Filippo Pucciani; Donato Francesco Altomare; Giuseppe Dodi; Guido Sciaudone; Ezio Falletto; Vittorio Piloni
Journal:  World J Gastroenterol       Date:  2012-09-28       Impact factor: 5.742

8.  An open-label, prospective clinical study to evaluate the efficacy and safety of TLPL/AY/01/2008 in the management of functional constipation.

Authors:  Renuka Munshi; Supriya Bhalerao; Pravin Rathi; V V Kuber; S U Nipanikar; K P Kadbhane
Journal:  J Ayurveda Integr Med       Date:  2011-07

Review 9.  Complementary and Alternative Therapies for Chronic Constipation.

Authors:  Xinjun Wang; Jieyun Yin
Journal:  Evid Based Complement Alternat Med       Date:  2015-05-03       Impact factor: 2.629

10.  Primary Care Management of Chronic Constipation in Asia: The ANMA Chronic Constipation Tool.

Authors:  Kok-Ann Gwee; Uday C Ghoshal; Sutep Gonlachanvit; Andrew Seng Boon Chua; Seung-Jae Myung; Shaman Rajindrajith; Tanisa Patcharatrakul; Myung-Gyu Choi; Justin C Y Wu; Min-Hu Chen; Xiao-Rong Gong; Ching-Liang Lu; Chien-Lin Chen; Nitesh Pratap; Philip Abraham; Xiao-Hua Hou; Meiyun Ke; Jane D Ricaforte-Campos; Ari Fahrial Syam; Murdani Abdullah
Journal:  J Neurogastroenterol Motil       Date:  2013-04-16       Impact factor: 4.924
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.