Literature DB >> 8234430

Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice.

C P Siegers1, J Siemers, G Baretton.   

Abstract

In a model of dimethylhydrazine-induced colorectal tumors in male mice aloin- or sennoside-enriched diets (0.03%) did not promote incidence and growth of adenomas and carcinomas after 20 weeks. Furthermore, in anthranoid-fed mice no significant changes in serum electrolytes as well as parameters of hepato- and nephrotoxicity were observed.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 8234430     DOI： 10.1159/000139859

Source DB:  PubMed          Journal:  Pharmacology        ISSN： 0031-7012            Impact factor:   2.547


  3 in total

1.  Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis miller (aloe vera) in F344/N rats.

Authors:  Mary D Boudreau; Paul W Mellick; Greg R Olson; Robert P Felton; Brett T Thorn; Frederick A Beland
Journal:  Toxicol Sci       Date:  2012-09-11       Impact factor: 4.849

2.  Toxicology and carcinogenesis study of senna in C3B6.129F1-Trp53 tm1Brd N12 haploinsufficient mice.

Authors:  Inok Surh; Amy Brix; John E French; Bradley J Collins; J Michael Sanders; Molly Vallant; June K Dunnick
Journal:  Toxicol Pathol       Date:  2012-11-02       Impact factor: 1.902

3.  Development of an LC-DAD-MS-Based Method for the Analysis of Hydroxyanthracene Derivatives in Food Supplements and Plant Materials.

Authors:  Francesca Loschi; Marta Faggian; Stefania Sut; Irene Ferrarese; Erica Maccari; Gregorio Peron; Stefano Dall'Acqua
Journal:  Molecules       Date:  2022-03-16       Impact factor: 4.411
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.