Literature DB >> 8233778

Studies on the synthesis of nucleotidyl-peptides. II. The preparation of a nucleotidyl-peptide having a 5'-nucleotidyl-(P-O)-serine phosphodiester bond.

Y Ueno1, R Saito, T Hata.   

Abstract

The preparation of a nucleotidyl-peptide having a thymidine-5'-yl-(P-O)-serine phosphodiester bond, [H-Ala-Ser(pTpT)-Phe-OH](24) is described. After condensation between the phosphorylated peptide component and an oligonucleotide component, all protecting groups could be removed under neutral conditions without beta-elimination of the pTpT from the serine moiety.

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Year:  1993        PMID： 8233778      PMCID： PMC311175          DOI： 10.1093/nar/21.19.4451

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  10 in total

1.  Protein is linked to the 5' end of poliovirus RNA by a phosphodiester linkage to tyrosine.

Authors:  V Ambros; D Baltimore
Journal:  J Biol Chem       Date:  1978-08-10       Impact factor: 5.157

2.  Nucleoside 3'-phosphotriesters as key intermediates for the oligoribonucleotide synthesis. IV. New method for removal of 2,2,2-trichloroethyl group and 31P NMR as a new tool for analysis of deblocking of internucleotide phosphate protecting groups.

Authors:  R W Adamiak; E Biala; R Kierzek; A Kraszewski; W T Markiewicz; J Stawiński
Journal:  Nucleic Acids Res       Date:  1977-07       Impact factor: 16.971

3.  O4-(5'-uridylyl)tyrosine is the bond between the genome-linked protein and the RNA of poliovirus.

Authors:  P G Rothberg; T J Harris; A Nomoto; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

4.  Adenovirus terminal protein precursor. Partial amino acid sequence and the site of covalent linkage to virus DNA.

Authors:  J E Smart; B W Stillman
Journal:  J Biol Chem       Date:  1982-11-25       Impact factor: 5.157

5.  Adenovirus DNA replication in vitro.

Authors:  M D Challberg; T J Kelly
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

6.  A model study directed towards the preparation of nucleopeptides via H-phosphonate intermediates.

Authors:  E Kuyl-Yeheskiely; C M Tromp; A H Schaeffer; G A van der Marel; J H van Boom
Journal:  Nucleic Acids Res       Date:  1987-02-25       Impact factor: 16.971

7.  Solid-phase synthesis of H-Phe-Tyr-(pATAT)-NH2: a nucleopeptide fragment from the nucleoprotein of bacteriophage phi X174.

Authors:  C M Dreef-Tromp; E M van Dam; H van den Elst; G A van der Marel; J H van Boom
Journal:  Nucleic Acids Res       Date:  1990-11-25       Impact factor: 16.971

8.  Synthesis of the nucleopeptides H-Phe-Tyr(pGC)-NH2 and H-Phe-Ser(pGC)-Ala-OH via a phosphotriester approach.

Authors:  E Kuyl-Yeheskiely; C M Dreef-Tromp; A Geluk; G A van der Marel; J H van Boom
Journal:  Nucleic Acids Res       Date:  1989-04-25       Impact factor: 16.971

9.  Solid-phase synthesis of the nucleopeptide fragment H-Asp-Ser[pAAAGTAAGCC]-Glu-OH from the nucleoprotein of Bacillus subtilis phage phi 29.

Authors:  C M Dreef-Tromp; J C van der Maarel; H van den Elst; G A van der Marel; J H van Boom
Journal:  Nucleic Acids Res       Date:  1992-08-11       Impact factor: 16.971

10.  Location of the serine residue involved in the linkage between the terminal protein and the DNA of phage phi 29.

Authors:  J M Hermoso; E Méndez; F Soriano; M Salas
Journal:  Nucleic Acids Res       Date:  1985-11-11       Impact factor: 16.971
  10 in total
  1 in total

1.  Solid-phase synthesis of a nucleopeptide from the linking site of adenovirus-2 nucleoprotein, -Ser(p5'CATCAT)-Gly-Asp-. Convergent versus stepwise strategy.

Authors:  J Robles; E Pedroso; A Grandas
Journal:  Nucleic Acids Res       Date:  1995-10-25       Impact factor: 16.971
  1 in total

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