| Literature DB >> 8233598 |
J Schrével1, C Barrault, A Deguercy, P Grellier, P Lawton, H G Heidrich, M Caballero, M Monsigny, R Mayer.
Abstract
Malarial proteinases of the erythrocytic life-cycle are used to design new inhibitors capable of blocking the parasite's development. The Merozoite Proteinase for Erythrocytic Invasion (MPEI) of Plasmodium falciparum, a neutral proteinase, and the acidic Pf37 proteinase acting on spectrin as substrate, are good candidates for this kind of strategy.Entities:
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Year: 1993 PMID: 8233598
Source DB: PubMed Journal: Parassitologia ISSN: 0048-2951