Arterial baroreceptor information affects striatal dopamine release measured by voltammetry in rats.

The effects of altering the arterial blood pressure on the extracellular levels of dopamine in the corpus striatum, measured using nafion-coated C fiber electrodes combined with differential pulse amperometry, were assessed in urethane-anesthetized rats. The striatal dopamine release was increased by increasing the carotid blood pressure with phenylephrine injection but decreased by decreasing the carotid blood pressure with bilateral carotid occlusion. The data indicate that baroreceptors inputs affect the striatal dopamine release in rats.