Literature DB >> 8230624

Rationing failure. The ethical lessons of the retransplantation of scarce vital organs.

P A Ubel1, R M Arnold, A L Caplan.   

Abstract

Because of a shortage of transplantable livers and hearts, the transplant community has had to decide--by who gets an organ--who lives or dies. Despite this shortage, whether one has previously received a transplant is not used as a criterion to distribute organs. The existing allocation system distributes 10% to 20% of available hearts and livers to retransplant patients. This article examines three differences between primary transplantation and retransplantation that may affect the priority that retransplant candidates should receive in vying for organs: (1) the special obligations that transplant teams have not to abandon patients on whom they have already performed a transplant, (2) the fairness of allowing individuals to get multiple transplants while some die awaiting their first, and (3) the difference in efficacy between primary transplantation and retransplantation. Only this last difference holds up to critical analysis. Our moral duty to direct scarce, lifesaving resources to those likely to benefit from them, suggests that, all other things equal, primary transplant candidates should receive priority because their mortality after transplantation is lower. Consistency also demands that previous transplant history be taken into account, as we already allocate organs according to ABO blood group matching, a factor that affects transplant outcome approximately the same amount as a previous transplantation. We therefore conclude that the system should be revised so that primary transplant candidates have a better chance of receiving organs than retransplant candidates.

Entities:  

Keywords:  Analytical Approach; Health Care and Public Health; United Network for Organ Sharing

Mesh:

Year:  1993        PMID: 8230624     DOI: 10.1001/jama.270.20.2469

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  20 in total

1.  Severity as an independent determinant of the social value of a health service.

Authors:  Jeff R J Richardson; John McKie; Stuart J Peacock; Angelo Iezzi
Journal:  Eur J Health Econ       Date:  2010-05-09

2.  Lung retransplantation.

Authors:  Steven M Kawut
Journal:  Clin Chest Med       Date:  2011-06       Impact factor: 2.878

3.  "The choice for death" and neurology.

Authors:  Anna Durnová; Herbert Gottweis
Journal:  J Neurol       Date:  2010-07       Impact factor: 4.849

4.  Can we direct organ allocation based on predicted outcome? Hepatocellular carcinoma outside of UCSF criteria or retransplant?

Authors:  Caroline Rochon; Patricia Sheiner; Basant Mahadevappa; Ganesh Gunasekaran; Joyti Sharma; David C Wolf; Marcelo Facciuto
Journal:  Langenbecks Arch Surg       Date:  2012-01-28       Impact factor: 3.445

5.  Futility and rationing in liver retransplantation: when and how can we say no?

Authors:  Scott W Biggins
Journal:  J Hepatol       Date:  2012-02-04       Impact factor: 25.083

6.  Wait list death and survival benefit of kidney transplantation among nonrenal transplant recipients.

Authors:  J R Cassuto; P P Reese; S Sonnad; R D Bloom; M H Levine; K M Olthoff; A Shaked; A Naji; P Abt
Journal:  Am J Transplant       Date:  2010-11       Impact factor: 8.086

7.  Expensive cancer drugs: a comparison between the United States and the United Kingdom.

Authors:  Ruth R Faden; Kalipso Chalkidou; John Appleby; Hugh R Waters; Jonathon P Leider
Journal:  Milbank Q       Date:  2009-12       Impact factor: 4.911

8.  An efficient method for kidney allocation problem: a credibility-based fuzzy common weights data envelopment analysis approach.

Authors:  Sahar Ahmadvand; Mir Saman Pishvaee
Journal:  Health Care Manag Sci       Date:  2017-08-09

9.  Rule of rescue or the good of the many? An analysis of physicians' and nurses' preferences for allocating ICU beds.

Authors:  Rachel Kohn; Gordon D Rubenfeld; Mitchell M Levy; Peter A Ubel; Scott D Halpern
Journal:  Intensive Care Med       Date:  2011-06-07       Impact factor: 17.440

10.  Hepatic retransplantation in cholestatic liver disease: impact of the interval to retransplantation on survival and resource utilization.

Authors:  W R Kim; R H Wiesner; J J Poterucha; T M Therneau; M Malinchoc; J T Benson; J S Crippin; G B Klintmalm; J Rakela; T E Starzl; R A Krom; R W Evans; E R Dickson
Journal:  Hepatology       Date:  1999-08       Impact factor: 17.425

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