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Literature DB >> 8229011

Structure of fischerin, a new toxic metabolite from an ascomycete, Neosartorya fischeri var. fischeri.

H Fujimoto¹, M Ikeda, K Yamamoto, M Yamazaki.

Abstract

A new toxic metabolite named fischerin [1] from an Ascomycete. Neosartorya fischeri var. fischeri, which caused lethal peritonitis in mice, was deduced to have a structure including a 1,4-dihydroxy-3,5-disubstituted-2(1H)-pyridone moiety by chemical and spectral data.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1993 PMID： 8229011 DOI： 10.1021/np50098a010

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

6 in total

1. Biomimetic conversion of (-)-fusoxypyridone and (-)-oxysporidinone to (-)-sambutoxin: further evidence for the structure of the tricyclic pyridone alkaloid, (-)-fusoxypyridone.

Authors: E M Kithsiri Wijeratne; A A Leslie Gunatilaka
Journal: Bioorg Med Chem Lett Date: 2011-03-16 Impact factor: 2.823

Review 2. Aspergillus fumigatus and aspergillosis: From basics to clinics.

Authors: A Arastehfar; A Carvalho; J Houbraken; L Lombardi; R Garcia-Rubio; J D Jenks; O Rivero-Menendez; R Aljohani; I D Jacobsen; J Berman; N Osherov; M T Hedayati; M Ilkit; D James-Armstrong; T Gabaldón; J Meletiadis; M Kostrzewa; W Pan; C Lass-Flörl; D S Perlin; M Hoenigl
Journal: Stud Mycol Date: 2021-05-10 Impact factor: 16.097

Structure of fischerin, a new toxic metabolite from an ascomycete, Neosartorya fischeri var. fischeri.

1. Biomimetic conversion of (-)-fusoxypyridone and (-)-oxysporidinone to (-)-sambutoxin: further evidence for the structure of the tricyclic pyridone alkaloid, (-)-fusoxypyridone.

Review 2. Aspergillus fumigatus and aspergillosis: From basics to clinics.

3. Dermatitis caused by Neosartorya hiratsukae infection in a hedgehog.

4. Bioactive Pyridone Alkaloids from a Deep-Sea-Derived Fungus Arthrinium sp. UJNMF0008.

Review 5. Bioactive Compounds from Terrestrial and Marine-Derived Fungi of the Genus Neosartorya †.

6. Polyphasic taxonomy of Aspergillus section Fumigati and its teleomorph Neosartorya.