Literature DB >> 8227249

Immune regulation: learning from leprosy.

R L Modlin1, B R Bloom.   

Abstract

The specific anergy seen in severe, disseminated leprosy appears to represent multifaceted actions of macrophages and suppressor T lymphocytes. Identification of cytokine mediation in these events helps to account for the immune system's "choice" of cellular versus humoral defenses--and points toward manipulation of cytokine switches for immunotherapy against infectious and autoimmune disease.

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Year:  1993        PMID: 8227249     DOI: 10.1080/21548331.1993.11442874

Source DB:  PubMed          Journal:  Hosp Pract (Off Ed)        ISSN: 8750-2836


  3 in total

Review 1.  Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases.

Authors:  D R Lucey; M Clerici; G M Shearer
Journal:  Clin Microbiol Rev       Date:  1996-10       Impact factor: 26.132

2.  Molecular evidence for two forms of Crohn disease.

Authors:  E C Gilberts; A J Greenstein; P Katsel; N Harpaz; R J Greenstein
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

Review 3.  Leprosy: review of the epidemiological, clinical, and etiopathogenic aspects - part 1.

Authors:  Joel Carlos Lastória; Marilda Aparecida Milanez Morgado de Abreu
Journal:  An Bras Dermatol       Date:  2014 Mar-Apr       Impact factor: 1.896

  3 in total

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