Loss of electrolytes during repair and regeneration of skeletal muscle.

Changes in the specific conductivity and electrolytes have been studied in the leachates from normal and minced autografted chick gastrocnemii with special reference to the loss of Na+, K+, Ca2+, Mg2+ and PO(4)3- ions. The study has revealed age related modifications in the muscle membranes as well as the presence of some intrinsic regulatory mechanisms which get stimulated under the induced-stress condition. Higher ionic efflux in the regenerating muscle indicates that the anatomical regeneration does not correspond to functional regeneration of muscle membranes.