Literature DB >> 822484

Biliary metabolites of 2,5,2',5'-tetrachlorobiphenyl in the rat.

D H Norback, J L Seymour, K M Knieriem, R E Peterson, J R Allen.   

Abstract

Biliary metabolites of rats receiving 3H labeled 2,5,2',5'-tetrachlorobiphenyl, a component of commercial polychlorinated bipheyl (PCB) mixtures include 3-OH-2,5,2',5'-tetrachlorobiphenyl and a dihydrodiol tentatively identified as trans-3,4-dihydrodihydroxy-2,5,2',5'-tetrachlorobiphenyl. Metabolism of PCBs in the rat probably occurs in part through an arene oxide intermediate.

Entities:  

Mesh:

Substances:

Year:  1976        PMID: 822484

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  2 in total

1.  Acute hepatotoxicity of a tetrachlorobiphenyl--changes in the hepatocyte ultrastructure and plasma membrane-bound enzymes.

Authors:  F S Lin; M T Hsia; J R Allen
Journal:  Arch Environ Contam Toxicol       Date:  1979       Impact factor: 2.804

2.  Polychlorinated biphenyl induction of hepatocellular carcinoma in the Sprague-Dawley rat.

Authors:  D H Norback; R H Weltman
Journal:  Environ Health Perspect       Date:  1985-05       Impact factor: 9.031

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.