Literature DB >> 8223469

Developmental precise excision of Oxytricha trifallax telomere-bearing elements and formation of circles closed by a copy of the flanking target duplication.

K Williams1, T G Doak, G Herrick.   

Abstract

The 4.1 kbp TBE1 elements of Oxytricha fallax and Oxytricha trifallax are deduced to transpose into a centrisymmetric target, CAnTG, and to duplicate the central AnT. Despite conserved C(A4C4)2 telomeric repeats at their tips, free TBE1s found during macronuclear development are not linear but 4.1 kbp circles closed on one copy of the AnT target duplication. The macronucleus-destined flanks are rejoined to regenerate the target, effecting efficient and precise somatic reversion of the germline transpositional mutation. A model is presented in which transposase catalyzes concerted precise rejoining of the flanks and cyclization of the excised element.

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Year:  1993        PMID： 8223469      PMCID： PMC413894          DOI： 10.1002/j.1460-2075.1993.tb06148.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  26 in total

Review 1.  The unusual organization and processing of genomic DNA in hypotrichous ciliates.

Authors:  D M Prescott
Journal:  Trends Genet       Date:  1992-12       Impact factor: 11.639

2.  Site-specific transposition of insertion sequence IS630.

Authors:  T Tenzen; S Matsutani; E Ohtsubo
Journal:  J Bacteriol       Date:  1990-07       Impact factor: 3.490

3.  Precise excision of telomere-bearing transposons during Oxytricha fallax macronuclear development.

Authors:  D J Hunter; K Williams; S Cartinhour; G Herrick
Journal:  Genes Dev       Date:  1989-12       Impact factor: 11.361

4.  Mobile elements bounded by C4A4 telomeric repeats in Oxytricha fallax.

Authors:  G Herrick; S Cartinhour; D Dawson; D Ang; R Sheets; A Lee; K Williams
Journal:  Cell       Date:  1985-12       Impact factor: 41.582

Review 5.  Multiple sequence versions of the Oxytricha fallax 81-MAC alternate processing family.

Authors:  G Herrick; S W Cartinhour; K R Williams; K P Kotter
Journal:  J Protozool       Date:  1987-11

6.  Internal sequences are eliminated from genes during macronuclear development in the ciliated protozoan Oxytricha nova.

Authors:  L A Klobutcher; C L Jahn; D M Prescott
Journal:  Cell       Date:  1984-04       Impact factor: 41.582

7.  Macronuclear DNA of the hypotrichous ciliate Oxytricha fallax.

Authors:  P M Rae; B B Spear
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

8.  Three different macronuclear DNAs in Oxytricha fallax share a common sequence block.

Authors:  S W Cartinhour; G A Herrick
Journal:  Mol Cell Biol       Date:  1984-05       Impact factor: 4.272

9.  A programmed site-specific DNA rearrangement in Tetrahymena thermophila requires flanking polypurine tracts.

Authors:  R Godiska; M C Yao
Journal:  Cell       Date:  1990-06-29       Impact factor: 41.582

10.  Target sequences for the C. elegans transposable element Tc1.

Authors:  B Rosenzweig; L W Liao; D Hirsh
Journal:  Nucleic Acids Res       Date:  1983-10-25       Impact factor: 16.971
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  39 in total

1.  A nuclear protein involved in apoptotic-like DNA degradation in Stylonychia: implications for similar mechanisms in differentiating and starved cells.

Authors:  C Maercker; H Kortwig; M A Nikiforov; C D Allis; H J Lipps
Journal:  Mol Biol Cell       Date:  1999-09       Impact factor: 4.138

2.  Timing of developmentally programmed excision and circularization of Paramecium internal eliminated sequences.

Authors:  M Bétermier; S Duharcourt; H Seitz; E Meyer
Journal:  Mol Cell Biol       Date:  2000-03       Impact factor: 4.272

3.  Product analysis illuminates the final steps of IES deletion in Tetrahymena thermophila.

Authors:  S V Saveliev; M M Cox
Journal:  EMBO J       Date:  2001-06-15       Impact factor: 11.598

4.  RNA-mediated epigenetic regulation of DNA copy number.

Authors:  Mariusz Nowacki; Joanna E Haye; Wenwen Fang; Vikram Vijayan; Laura F Landweber
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-15       Impact factor: 11.205

5.  A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common "D35E" motif.

Authors:  T G Doak; F P Doerder; C L Jahn; G Herrick
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-01       Impact factor: 11.205

Review 6.  The area code hypothesis revisited: olfactory receptors and other related transmembrane receptors may function as the last digits in a cell surface code for assembling embryos.

Authors:  W J Dreyer
Journal:  Proc Natl Acad Sci U S A       Date:  1998-08-04       Impact factor: 11.205

Review 7.  Insertion sequences.

Authors:  J Mahillon; M Chandler
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

8.  Processing of double-strand breaks is involved in the precise excision of paramecium internal eliminated sequences.

Authors:  Ariane Gratias; Mireille Bétermier
Journal:  Mol Cell Biol       Date:  2003-10       Impact factor: 4.272

9.  Consensus inverted terminal repeat sequence of Paramecium IESs: resemblance to termini of Tc1-related and Euplotes Tec transposons.

Authors:  L A Klobutcher; G Herrick
Journal:  Nucleic Acids Res       Date:  1995-06-11       Impact factor: 16.971

10.  Developmentally regulated chromosome fragmentation linked to imprecise elimination of repeated sequences in paramecia.

Authors:  Anne Le Mouël; Alain Butler; François Caron; Eric Meyer
Journal:  Eukaryot Cell       Date:  2003-10
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