Literature DB >> 8222868

Silver sulphadiazine: a comprehensive in vitro reassessment.

J M Hamilton-Miller1, S Shah, C Smith.   

Abstract

The antimicrobial activity of silver sulphadiazine has been determined agonist 409 strains from 12 different genera. MICs were usually in the range 16-64 micrograms/ml. Multi-resistant species, such as methicillin-resistant Staphylococcus aureus and Acinetobacter spp., were uniformly sensitive. MICs always exceeded the reported aqueous solubility of silver sulphadiazine. No resistant strains were found, and there was no correlation between MIC of silver sulphadiazine and resistance to sulphonamides. Time-kill experiments showed that sulphonamide-resistant S. aureus (but not Staphylococcus epidermidis) were killed significantly more slowly than were sulphonamide-sensitive strains.

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Year:  1993        PMID： 8222868     DOI： 10.1159/000238985

Source DB:  PubMed          Journal:  Chemotherapy        ISSN： 0009-3157            Impact factor:   2.544


  6 in total

Review 1.  Silver-containing alginate fibres and dressings.

Authors:  Yimin Qin
Journal:  Int Wound J       Date:  2005-06       Impact factor: 3.315

2.  Direct evidence for uptake of intact liposomes encapsulating silver sulfadiazine by cultured human keratinocytes based on combined transmission electron microscopy and X-ray microanalysis.

Authors:  M Schaller; R Wurm; H C Korting
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

3.  Bacterial inactivation using silver-coated magnetic nanoparticles as functional antimicrobial agents.

Authors:  Lingyan Wang; Jin Luo; Shiyao Shan; Elizabeth Crew; Jun Yin; Chuan-Jian Zhong; Brandi Wallek; Season S S Wong
Journal:  Anal Chem       Date:  2011-10-14       Impact factor: 6.986

4.  Disposition of intravenously or orally administered silver nanoparticles in pregnant rats and the effect on the biochemical profile in urine.

Authors:  Timothy R Fennell; Ninell P Mortensen; Sherry R Black; Rodney W Snyder; Keith E Levine; Eric Poitras; James M Harrington; Christopher J Wingard; Nathan A Holland; Wimal Pathmasiri; Susan C J Sumner
Journal:  J Appl Toxicol       Date:  2016-10-03       Impact factor: 3.446

5.  Chitosan and alginate polyelectrolyte complex membranes and their properties for wound dressing application.

Authors:  Xin Meng; Feng Tian; Jian Yang; Chun-Nian He; Nan Xing; Fan Li
Journal:  J Mater Sci Mater Med       Date:  2010-01-26       Impact factor: 3.896

6.  Effects of Silver Sulphadiazine on Production of Extracellular Proteins by Strains of Staphylococcus Aureus Isolated from Burns Wound.

Authors:  Vahideh Javid Khojasteh; Souad Alfakhri; Howard Anthony Foster
Journal:  Iran J Pharm Res       Date:  2016       Impact factor: 1.696
  6 in total

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