Literature DB >> 8222738

An improved ocular perfusion system.

C R Ethier1, P Ajersch, R Pirog.   

Abstract

We describe the design, construction and testing of an improved ocular perfusion system for outflow facility measurement. The essential feature of the system is the measurement of a differential pressure across a calibrated length of tubing, which provides a stable and accurate reading of facility and hence also of flowrate. Perfusion of calibrated lengths of tubing showed excellent accuracy, while perfusions of enucleated eyes showed very low noise levels. The system is relatively inexpensive, easy to construct and maintain, insensitive to vibrations and other noise, and accurate. It is therefore felt to be superior to conventional "hanging bucket" ocular perfusion systems.

Mesh:

Year:  1993        PMID: 8222738     DOI: 10.3109/02713689308995773

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN: 0271-3683            Impact factor:   2.424


  7 in total

1.  Biomechanics of Schlemm's canal endothelial cells: influence on F-actin architecture.

Authors:  C Ross Ethier; A Thomas Read; Darren Chan
Journal:  Biophys J       Date:  2004-10       Impact factor: 4.033

2.  S1P₂ receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology.

Authors:  Grant M Sumida; W Daniel Stamer
Journal:  Am J Physiol Cell Physiol       Date:  2011-02-02       Impact factor: 4.249

3.  Colocalization of outflow segmentation and pores along the inner wall of Schlemm's canal.

Authors:  Sietse T Braakman; A Thomas Read; Darren W-H Chan; C Ross Ethier; Darryl R Overby
Journal:  Exp Eye Res       Date:  2014-11-13       Impact factor: 3.467

4.  Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes.

Authors:  W Daniel Stamer; A Thomas Read; Grant M Sumida; C Ross Ethier
Journal:  Exp Eye Res       Date:  2009-08-27       Impact factor: 3.467

5.  Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia.

Authors:  Saumya S VanderWyst; Kristin M Perkumas; A Thomas Read; Darryl R Overby; W Daniel Stamer
Journal:  Mol Vis       Date:  2011-01-19       Impact factor: 2.367

6.  Application of an organotypic ocular perfusion model to assess intravitreal drug distribution in human and animal eyes.

Authors:  D Chan; G J Won; A T Read; C R Ethier; E Thackaberry; S R Crowell; H Booler; V Bantseev; J M Sivak
Journal:  J R Soc Interface       Date:  2022-01-26       Impact factor: 4.118

7.  Measurement of Outflow Facility Using iPerfusion.

Authors:  Joseph M Sherwood; Ester Reina-Torres; Jacques A Bertrand; Barnaby Rowe; Darryl R Overby
Journal:  PLoS One       Date:  2016-03-07       Impact factor: 3.240

  7 in total

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