| Literature DB >> 8221063 |
J Kawagoe1, K Abe, M Aoki, K Kogure.
Abstract
Distribution of heat shock protein (HSP) 90 alpha mRNA induction after 10 min of transient global ischemia was investigated in gerbil hippocampus by in situ hybridization. A small amount of HSP90 alpha mRNA was normally present in hippocampal cells and the mRNA was further induced with a peak at 8 h after ischemia. In hippocampal CA1 cells that are vulnerable to ischemia, HSP90 alpha mRNA was continuously induced by 1 day and finally diminished at 2 days. The temporal profile of HSP90 alpha mRNA induction in hippocampal CA1 cells was similar to that of HSP70 mRNA reported previously, suggesting a cooperative role of HSP90 alpha with other HSPs after ischemia.Entities:
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Year: 1993 PMID： 8221063 DOI： 10.1016/0006-8993(93)90306-8
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252