Literature DB >> 8219997

[The characteristics of the wound-healing action of solubilized alpha-tocopherol acetate].

A V Samoĭlov, R D Seĭfulla, A B Shekhter, A I Volozhin, A B Denisov, R A Druzhinina, E N Pomerantseva, N O Kamaev, M V Belous.   

Abstract

The rat experiments were made to compare the wound-healing action of solubilized (aqueous) alpha-tocopherol acetate (SATA) prepared by the original techniques and its official oil-based preparation. A course intravenous SATA (2 mg four times at an interval of 4 days) administration was found to stimulate epithelial regeneration and suppress the formation of connective tissue of uncomplicated skin wounds. By healing the complicated wounds, SATA potentiated the occurrence of an inflammatory reaction and slowed down regeneration, whereas its oily solution failed to produce this effect.

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Year:  1993        PMID: 8219997

Source DB:  PubMed          Journal:  Eksp Klin Farmakol        ISSN: 0869-2092


  1 in total

1.  Design and optimization of a novel herbosomal-loaded PEG-poloxamer topical formulation for the treatment of cold injuries: a quality-by-design approach.

Authors:  Renu BalaYadav; Dharam Pal Pathak; Rajeev Varshney; Rajesh Arora
Journal:  Drug Deliv Transl Res       Date:  2022-04-21       Impact factor: 5.671

  1 in total

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