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Literature DB >> 8219847

Subclinical hypothyroidism. To treat or not to treat.

E A Laryea¹.
1. McGill University, Montreal.

Abstract

The term subclinical hypothyroidism has been used to describe the syndrome of high serum levels of thyroid-stimulating hormone associated with normal levels of thyroid hormone. Diagnosis requires a sensitive method of measuring TSH. Because the syndrome does not invariably lead to overt hypothyroidism, it would not be appropriate to institute lifelong levothyroxine therapy in every case. Cases that do not qualify for immediate therapy need close follow up.

Entities: Chemical Disease

Mesh：

Substances：
Thyrotropin
Thyroxine

Year: 1993 PMID： 8219847 PMCID： PMC2379904

Source DB: PubMed Journal: Can Fam Physician ISSN： 0008-350X Impact factor: 3.275

21 in total

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Authors: W H LLOYD; I J GOLDBERG
Journal: Br Med J Date: 1961-11-11

2. A double-blind cross-over 12-month study of L-thyroxine treatment of women with 'subclinical' hypothyroidism.

Authors: E Nyström; K Caidahl; G Fager; C Wikkelsö; P A Lundberg; G Lindstedt
Journal: Clin Endocrinol (Oxf) Date: 1988-07 Impact factor: 3.478

3. Coronary-artery disease in hypothyroidism.

Authors: P A Bastenie; L Vanhaelst; P Neve
Journal: Lancet Date: 1967-12-09 Impact factor: 79.321

4. Clinical and pathological significance of asymptomatic atrophic thyroiditis. A condition of latent hypothyroidism.

Authors: P A Bastenie; M Bonnyns; P Neve; L Vanhaelst; M Chailly
Journal: Lancet Date: 1967-04-29 Impact factor: 79.321

5. Improved radioimmunoassay for human TSH.

Authors: C A Spencer; J T Nicoloff
Journal: Clin Chim Acta Date: 1980-12-22 Impact factor: 3.786

6. L-Thyroxine therapy in subclinical hypothyroidism. A double-blind, placebo-controlled trial.

Authors: D S Cooper; R Halpern; L C Wood; A A Levin; E C Ridgway
Journal: Ann Intern Med Date: 1984-07 Impact factor: 25.391

7. Marked hyperprolactinemia in subclinical hypothyroidism.

Authors: K E Olive; J V Hennessey
Journal: Arch Intern Med Date: 1988-10

8. The aging thyroid. Increased prevalence of elevated serum thyrotropin levels in the elderly.

Authors: C T Sawin; D Chopra; F Azizi; J E Mannix; P Bacharach
Journal: JAMA Date: 1979-07-20 Impact factor: 56.272

9. Grades of hypothyroidism.

Authors: D C Evered; B J Ormston; P A Smith; R Hall; T Bird
Journal: Br Med J Date: 1973-03-17

Review 10. Clinical utility and cost-effectiveness of sensitive thyrotropin assays in ambulatory and hospitalized patients.

Authors: C A Spencer
Journal: Mayo Clin Proc Date: 1988-12 Impact factor: 7.616

2 in total

1. Outcome of treating hypothyroidism.

Authors: S Katz
Journal: Can Fam Physician Date: 1993-12 Impact factor: 3.275

2. Urinary cortisol metabolites in the assessment of peripheral thyroid hormone action: overt and subclinical hypothyroidism.

Authors: M C Vantyghem; A Ghulam; C Hober; C Schoonberg; M D'Herbomez; A Racadot; A Boersma; J Lefebvre
Journal: J Endocrinol Invest Date: 1998-04 Impact factor: 4.256

2 in total