Literature DB >> 821961

Thyroid-stimulating immunoglobulins and the control of thyroid function.

R Clague, E D Mukhtar, G A Pyle, J Nutt, F Clark, M Scott, D Evered, B R Smith, R Hall.   

Abstract

Triiodothyronine (T3) suppression and thyrotropin-releasing hormone (TRH) tests were used to study thyroid function in 50 patients with thyroid disease. The results of the thyroid function tests were compared with the levels of serum thyroid-stimulating immunoglobulins (TSI) measured by a radio-receptor assay. In euthyroid and hyperthyroid patients, the presence of TSI corresponded with the absence of TSH control of thyroid function. However, in two hypothyroid patients with serum TSI levels readily detectable in the receptor assay, T3 suppression and TRH tests indicated that thyroid function was under TSH control.

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Year:  1976        PMID： 821961     DOI： 10.1210/jcem-43-3-550

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  6 in total

1.  TSH-receptor antibodies, HLA B8 and thyroid autoantibodies in patients with Graves' disease in therapeutically induced euthyroidism.

Authors:  G Schernthaner; H Ludwig; H Schleusener; R Finke; P Kotulla; W R Mayr
Journal:  Experientia       Date:  1979-10-15

2.  Goiter: an approach to management.

Authors:  W C Nicholas
Journal:  Can Fam Physician       Date:  1978-04       Impact factor: 3.275

3.  Response to TRH, serum thyroid hormone concentration, and serum markers of autoimmunity after antithyroid therapy in Graves' disease.

Authors:  B A Lamberg; A Aro; P Saarinen; T Tötterman; T Mäkinen
Journal:  J Endocrinol Invest       Date:  1978-01       Impact factor: 4.256

4.  Determination of thyroid stimulating immunoglobulins (TSI) during the course of Graves' disease. A reliable indicator for remission and persistence of this disease?

Authors:  H Schleusener; R Finke; P Kotulla; K W Wenzel; H Meinhold; H D Roedler
Journal:  J Endocrinol Invest       Date:  1978-04       Impact factor: 4.256

5.  Changes in thyrotropin binding inhibiting immunoglobulins (TBII) in sera of patients with Graves' disease at the time of relapse or exacerbation.

Authors:  H Uchimura; N Akimoto; T Mitsuhashi; K Kubota; N Kuzuya; Y Imai; H Ikeda; F Matsuzaki; L F Kumagai
Journal:  J Endocrinol Invest       Date:  1986-02       Impact factor: 4.256

Review 6.  The impact of peptide hormone receptor research on clinical medicine.

Authors:  T F Davies
Journal:  J R Coll Physicians Lond       Date:  1978-07
  6 in total

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