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Literature DB >> 8219048

A point mutation in the chloroplast rps12 gene from Nicotiana plumbaginifolia confers streptomycin resistance.

C M Hsu¹, W P Yang, C C Chen, Y K Lai, T Y Lin.

Abstract

In an effort to understand the mechanism of streptomycin resistance in Nicotiana plumbaginifolia, we have sequenced the chloroplast rps12 gene, a potential molecular target. We report that a streptomycin-resistant mutant isolated from protoplast cultures of N. plumbaginifolia contains an A-to-G transition at nucleotide position 149 in exon 2 of the chloroplast rps12 gene. The detected point mutation predicts a substitution of arginine for lysine in a phylogenetically conserved region.

Entities: Chemical Mutation Species

Mesh：

Substances：

Year: 1993 PMID： 8219048 DOI： 10.1007/bf00021429

Source DB: PubMed Journal: Plant Mol Biol ISSN： 0167-4412 Impact factor: 4.076

19 in total

1. Restriction endonuclease analysis of chloroplast DNA from streptomycin-resistant mutants of Nicotiana plumbaginifolia.

Authors: K Y To; Y K Lai; T Y Feng; C C Chen
Journal: Genome Date: 1992-04 Impact factor: 2.166

2. Interaction between 16S ribosomal RNA and ribosomal protein S12: differential effects of paromomycin and streptomycin.

Authors: M O'Connor; E A De Stasio; A E Dahlberg
Journal: Biochimie Date: 1991-12 Impact factor: 4.079

3. Ribosomal protein S12 as a site for streptomycin resistance in Nicotiana chloroplasts.

Authors: S Galili; H Fromm; D Aviv; M Edelman; E Galun
Journal: Mol Gen Genet Date: 1989-08

4. Identification and functional characterization of the protein controlled by the streptomycin-resistant locus in E. coli.

Authors: M Ozaki; S Mizushima; M Nomura
Journal: Nature Date: 1969-04-26 Impact factor: 49.962

5. Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: correlation of genetic and physical maps of the chloroplast genome.

Authors: E H Harris; B D Burkhart; N W Gillham; J E Boynton
Journal: Genetics Date: 1989-10 Impact factor: 4.562

6. Trans-splicing in chloroplasts: the rps 12 loci of Nicotiana tabacum.

Authors: M Hildebrand; R B Hallick; C W Passavant; D P Bourque
Journal: Proc Natl Acad Sci U S A Date: 1988-01 Impact factor: 11.205

7. Streptomycin-resistance of Euglena gracilis chloroplasts: identification of a point mutation in the 16S rRNA gene in an invariant position.

Authors: P E Montandon; P Nicolas; P Schürmann; E Stutz
Journal: Nucleic Acids Res Date: 1985-06-25 Impact factor: 16.971

4. Complete Chloroplast Genome Sequence of Fagus longipetiolata Seemen (Fagaceae): Genome Structure, Adaptive Evolution, and Phylogenetic Relationships.

Authors: Daqu Liang; Haoyun Wang; Jun Zhang; Yuanxiang Zhao; Feng Wu
Journal: Life (Basel) Date: 2022-01-09

4 in total

A point mutation in the chloroplast rps12 gene from Nicotiana plumbaginifolia confers streptomycin resistance.

1. Restriction endonuclease analysis of chloroplast DNA from streptomycin-resistant mutants of Nicotiana plumbaginifolia.

2. Interaction between 16S ribosomal RNA and ribosomal protein S12: differential effects of paromomycin and streptomycin.

3. Ribosomal protein S12 as a site for streptomycin resistance in Nicotiana chloroplasts.

4. Identification and functional characterization of the protein controlled by the streptomycin-resistant locus in E. coli.

5. Antibiotic resistance mutations in the chloroplast 16S and 23S rRNA genes of Chlamydomonas reinhardtii: correlation of genetic and physical maps of the chloroplast genome.

6. Trans-splicing in chloroplasts: the rps 12 loci of Nicotiana tabacum.

7. Streptomycin-resistance of Euglena gracilis chloroplasts: identification of a point mutation in the 16S rRNA gene in an invariant position.

8. Isolation and characterization of streptomycin-resistant mutants in Nicotiana plumbaginifolia.

9. E. coli ribosomes with a C912 to U base change in the 16S rRNA are streptomycin resistant.

10. A functional pseudoknot in 16S ribosomal RNA.

1. Experimental reconstruction of functional gene transfer from the tobacco plastid genome to the nucleus.

Review 2. Chloroplast ribosomes and protein synthesis.

3. Point mutations in the chloroplast 16s rRNA gene confer streptomycin resistance in Nicotiana plumbaginifolia.

4. Complete Chloroplast Genome Sequence of Fagus longipetiolata Seemen (Fagaceae): Genome Structure, Adaptive Evolution, and Phylogenetic Relationships.