Literature DB >> 8217766

Serious childhood angiomas: unsuccessful alpha-2b interferon treatment. A report of four cases.

D Teillac-Hamel1, Y De Prost, C Bodemer, P Andry, O Enjolras, G Sebag, F Brunelle, P Hubert, C Nihoul-Fekete.   

Abstract

Over a 4-year period, we managed four children with alarming haemangiomas (two cases of Kasabach-Merritt syndrome and two life-threatening haemangiomas). Systemic steroid therapy was ineffective. Other treatments (radiotherapy, anti-platelet drugs) were also ineffective in the Kasabach-Merritt patients. On the basis of recent reports on the effects of interferon on endothelial cells, we used alpha-2 interferon therapy, but obtained no response.

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Year:  1993        PMID: 8217766     DOI: 10.1111/j.1365-2133.1993.tb03181.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  2 in total

1.  Megadose methylprednisolone for Kasabach-Merritt syndrome.

Authors:  S Ozsoylu
Journal:  Eur J Pediatr       Date:  1996-02       Impact factor: 3.183

2.  Cavernous haemangioma with Kasabach-Merritt syndrome: treatment with alpha-interferon.

Authors:  J J Ettlinger; P J Fleming; H S Joffe; C T Kennedy
Journal:  J R Soc Med       Date:  1996-01       Impact factor: 18.000

  2 in total

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