Literature DB >> 8213906

Julia Pastrana, the nondescript: an example of congenital, generalized hypertrichosis terminalis with gingival hyperplasia.

J Bondeson1, A E Miles.   

Abstract

Julia Pastrana (1834-1860) has gained immortality as one of the most extreme cases of generalized hypertrichosis upon record. When she was exhibited for money in the United States and Europe during the years 1855-1860, people thronged to see her, and she was several times described in the medical press of the day. After Julia Pastrana's death in childbirth, her corpse was embalmed in a very life-like manner, and exhibited all over Europe for several decades. Later, the mummy was believed to be lost, but in 1990 it was discovered at the Oslo Forensic Institute. Some writers have included Julia Pastrana among the cases of congenital hypertrichosis languinosa. However, a microscopic examination of hair samples from the mummy shows that her hairy growth is unmistakably terminal in character, and we propose that she instead was an example of congenital, generalized hypertrichosis terminalis with associated gingival hyperplasia. While many earlier writers have asserted that Julia Pastrana's dentition was abnormal, a radiographic examination of the mummy has shown that she had a complete permanent dentition.

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Year:  1993        PMID: 8213906     DOI: 10.1002/ajmg.1320470213

Source DB:  PubMed          Journal:  Am J Med Genet        ISSN: 0148-7299


  7 in total

1.  Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia.

Authors:  Miao Sun; Ning Li; Wu Dong; Zugen Chen; Qing Liu; Yiming Xu; Guang He; Yongyong Shi; Xin Li; Jiajie Hao; Yang Luo; Dandan Shang; Dan Lv; Fen Ma; Dai Zhang; Rui Hua; Chaoxia Lu; Yaran Wen; Lihua Cao; Alan D Irvine; W H Irwin McLean; Qi Dong; Ming-Rong Wang; Jun Yu; Lin He; Wilson H Y Lo; Xue Zhang
Journal:  Am J Hum Genet       Date:  2009-05-21       Impact factor: 11.025

Review 2.  [Genetic hair diseases. An update].

Authors:  J Frank; P Poblete-Gutiérrez; K Giehl
Journal:  Hautarzt       Date:  2013-11       Impact factor: 0.751

3.  An autosomal dominant syndrome of acromegaloid facial appearance and generalised hypertrichosis terminalis.

Authors:  A D Irvine; O M Dolan; D R Hadden; F J Stewart; E A Bingham; N C Nevin
Journal:  J Med Genet       Date:  1996-11       Impact factor: 6.318

4.  The hairy family of Burma: a four generation pedigree of congenital hypertrichosis lanuginosa.

Authors:  J Bondeson; A E Miles
Journal:  J R Soc Med       Date:  1996-07       Impact factor: 18.000

5.  Congenital Generalized Hypertrichosis, Gingival Hyperplasia, a Coarse Facies with Constriction Bands: A Rare Association.

Authors:  Aditya Kumar Bubna; Mahalakshmi Veeraraghavan; Sankarasubramaniam Anandan; Sudha Rangarajan
Journal:  Int J Trichology       Date:  2015 Apr-Jun

Review 6.  Congenital generalized hypertrichosis: the skin as a clue to complex malformation syndromes.

Authors:  Piero Pavone; Andrea D Praticò; Raffaele Falsaperla; Martino Ruggieri; Marcella Zollino; Giovanni Corsello; Giovanni Neri
Journal:  Ital J Pediatr       Date:  2015-08-05       Impact factor: 2.638

Review 7.  Gingival fibromatosis: clinical, molecular and therapeutic issues.

Authors:  Katarzyna Gawron; Katarzyna Łazarz-Bartyzel; Jan Potempa; Maria Chomyszyn-Gajewska
Journal:  Orphanet J Rare Dis       Date:  2016-01-27       Impact factor: 4.123

  7 in total

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