| Literature DB >> 82138 |
M R Keighley, D W Burdon, J Alexander-Williams, N Shinagawa, Y Arabi, H Thompson, D Youngs, S Bentley, R H George.
Abstract
241 patients who had gastrointestinal operations were studied prospectively. Postoperative diarrhoea occurred in 58 patients (24%) and was significantly more common after exposure to antibiotics. 9 patients (4%) had high titres of a neutralisable faecal toxin characteristic of pseudomembranous colitis. Toxigenic Clostridium difficile strains were isolated from the stools of all patients with neutralisable faecal toxin. If pseudomembranous colitis is defined as the presence of neutralisable faecal toxin, then the diagnosis is often missed by sigmoidoscopy and rectal biopsy.Entities:
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Year: 1978 PMID： 82138 DOI： 10.1016/s0140-6736(78)92151-7
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321