Literature DB >> 8213720

Exacerbation of psoriasis due to interferon-alpha treatment of chronic active hepatitis.

M J Georgetson1, J C Yarze, A T Lalos, G F Webster, P Martin.   

Abstract

Interferon-alpha is an immune modulating drug which is indicated for the treatment of chronic viral hepatitis B and C. Several previous reports have suggested an association between treatment of patients with interferon-alpha and the development or exacerbation of autoimmune diseases. We report two patients with chronic viral hepatitis in whom treatment with interferon-alpha was associated with dramatic worsening of previously diagnosed psoriasis, necessitating discontinuation of the drug.

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Year:  1993        PMID： 8213720

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN： 0002-9270            Impact factor:   10.864


  4 in total

Review 1.  Induction and exacerbation of psoriasis with Interferon-alpha therapy for hepatitis C: a review and analysis of 36 cases.

Authors:  M Afshar; A D Martinez; R L Gallo; T R Hata
Journal:  J Eur Acad Dermatol Venereol       Date:  2012-06-01       Impact factor: 6.166

Review 2.  Cytokine-induced autoimmune disorders.

Authors:  P Miossec
Journal:  Drug Saf       Date:  1997-08       Impact factor: 5.606

3.  Extensive psoriasis induced by pegylated interferon alfa-2a and ribavirin in the treatment of chronic hepatitis C.

Authors:  Gun-Wook Kim; Seung-Wook Jwa; Margaret Song; Hoon-Soo Kim; Byung-Soo Kim; Moon-Bum Kim; Hyun-Chang Ko
Journal:  Ann Dermatol       Date:  2013-11-30       Impact factor: 1.444

4.  The Clinical Significance of Autoantibodies in Hepatitis C Patients Submitted to Interferon Treatment.

Authors:  Eduardo Rodrigues-Pinto; Helder Cardoso; Sofia Pimenta; Guilherme Macedo
Journal:  GE Port J Gastroenterol       Date:  2015-01-12
  4 in total

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