Literature DB >> 821345

Malignant external otitis: a severe form of otitis in diabetic patients.

D A Zaky, D W Bentley, K Lowy, R F Betts, R G Douglas.   

Abstract

Two cases of malignant external otitis are presented and the literature is reviewed. The disease seems to occur exclusively in elderly diabetic patients. Diagnosis is mostly a clinical one, and requires a high index of suspicion. The characteristic clinical manifestations are pain and severe tenderness of the tissues around the ear and mastoid, persistent drainage and the presence of granulation tissue at the junction of the osseus and cartilagenous portions of the external ear. Roentgenographic findings are not helpful in the early stages. The pathogenesis of this disease depends on the presence of clefts in the cartilage forming the floor of the external auditory canal at its junction with the osseus portion through which infection can spread from the external ear to the deep soft tissues. Serious and often fatal complications may ensue. The most common and earliest symptom to appear if facial nerve palsy. Pseudomonas aeruginosa has been isolated uniformly, in pure or mixed cultures. This entity, therefore, should be borne in mind whenever an elderly diabetic patient presents with external otitis not amenable to the usual methods of therapy. Ps. aeruginosa should be strongly suspected, and its isolation should prompt vigorous systemic treatment with gentamicin and carbenicillin before extensive necrosis of cartilage and bone takes place. Any delay in diagnosis and management will lead to a serious and often fatal complications.

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Year:  1976        PMID: 821345     DOI: 10.1016/0002-9343(76)90181-9

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  12 in total

1.  Right ear pain and neck swelling.

Authors:  H Kirkpatrick; R E Jones; V Wadlington; J M Gilsoul
Journal:  Proc (Bayl Univ Med Cent)       Date:  2001-04

2.  Malignant pseudomonas external otitis.

Authors:  J E Edwards; W A Combs; L B Guze
Journal:  West J Med       Date:  1979-09

3.  Treating malignant otitis with oral ciprofloxacin.

Authors:  S A Hickey; G R Ford; A F O'Connor; S J Eykyn; P H Sönksen
Journal:  BMJ       Date:  1989-08-26

4.  The effect of diabetes mellitus on chronic rhinosinusitis and sinus surgery outcome.

Authors:  Zi Zhang; Nithin D Adappa; Ebbing Lautenbach; Alexander G Chiu; Laurel Doghramji; Timothy J Howland; Noam A Cohen; James N Palmer
Journal:  Int Forum Allergy Rhinol       Date:  2014-01-10       Impact factor: 3.858

5.  Infection and diabetes mellitus.

Authors: 
Journal:  West J Med       Date:  1979-06

Review 6.  Diabetes mellitus and infection.

Authors:  J G Larkin; B M Frier; J T Ireland
Journal:  Postgrad Med J       Date:  1985-03       Impact factor: 2.401

Review 7.  Diabetes in the elderly--a neglected area?

Authors:  R B Tattersall
Journal:  Diabetologia       Date:  1984-08       Impact factor: 10.122

8.  Staphylococcal malignant external otitis.

Authors:  P Bayardelle; M Jolivet-Granger; D Larochelle
Journal:  Can Med Assoc J       Date:  1982-01-15       Impact factor: 8.262

Review 9.  Management of peripheral facial nerve palsy.

Authors:  Josef Finsterer
Journal:  Eur Arch Otorhinolaryngol       Date:  2008-03-27       Impact factor: 2.503

10.  A tale of two risks: smoking, diabetes and the subgingival microbiome.

Authors:  Sukirth M Ganesan; Vinayak Joshi; Megan Fellows; Shareef M Dabdoub; Haikady N Nagaraja; Benjamin O'Donnell; Neeta Rohit Deshpande; Purnima S Kumar
Journal:  ISME J       Date:  2017-05-23       Impact factor: 10.302

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