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Literature DB >> 8213309

Synthesis of L-carnitine by microorganisms and isolated enzymes.

Abstract

L-Carnitine, a quaternary ammonium compound, plays an important role in beta-oxidation of fatty acids in mammals. The increasing demand for this compound in medicine has led to the development of numerous procedures for L-carnitine production. This review discusses the possibilities of microbial and enzymatical synthesis of L-carnitine and gives an overview on the pathways of L-carnitine metabolism and related enzymes in microorganisms.

Entities: Chemical

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Year: 1993 PMID： 8213309 DOI： 10.1007/bfb0007385

Source DB: PubMed Journal: Adv Biochem Eng Biotechnol ISSN： 0724-6145 Impact factor: 2.635

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Cited

9 in total

1. Identification and characterization of the caiF gene encoding a potential transcriptional activator of carnitine metabolism in Escherichia coli.

Authors: K Eichler; A Buchet; R Lemke; H P Kleber; M A Mandrand-Berthelot
Journal: J Bacteriol Date: 1996-03 Impact factor: 3.490

2. Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.

Authors: A Buchet; K Eichler; M A Mandrand-Berthelot
Journal: J Bacteriol Date: 1998-05 Impact factor: 3.490

3. L-carnitine Derived Zwitterionic Betaine Materials.

Authors: Wei Wang; Jianhai Yang; Ershuai Zhang; Yang Lu; Zhiqiang Cao
Journal: J Mater Chem B Date: 2017-10-20 Impact factor: 6.331

4. Role of carnitine in adaptation of Chromohalobacter salexigens DSM 3043 and its mutants to osmotic and temperature stress in defined medium.

Authors: Xiang-Lin Meng; Xia Gao; Yuan-Ming Si; Li-Li Xu; Li-Zhong Guo; Wei-Dong Lu
Journal: Extremophiles Date: 2022-08-14 Impact factor: 3.035

5. Carnitine resembles choline in the induction of cholinesterase, acid phosphatase, and phospholipase C and in its action as an osmoprotectant in Pseudomonas aeruginosa.

Authors: G I Lucchesi; T A Lisa; C H Casale; C E Domenech
Journal: Curr Microbiol Date: 1995-01 Impact factor: 2.188

Synthesis of L-carnitine by microorganisms and isolated enzymes.

1. Identification and characterization of the caiF gene encoding a potential transcriptional activator of carnitine metabolism in Escherichia coli.

2. Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.

3. L-carnitine Derived Zwitterionic Betaine Materials.

4. Role of carnitine in adaptation of Chromohalobacter salexigens DSM 3043 and its mutants to osmotic and temperature stress in defined medium.

5. Carnitine resembles choline in the induction of cholinesterase, acid phosphatase, and phospholipase C and in its action as an osmoprotectant in Pseudomonas aeruginosa.

6. Crotonobetaine reductase from Escherichia coli--a new inducible enzyme of anaerobic metabolization of L(-)-carnitine.

7. Comparison of the functional properties of trimeric and monomeric CaiT of Escherichia coli.

8. Metabolic engineering for high yielding L(-)-carnitine production in Escherichia coli.

9. Production of L-carnitine by secondary metabolism of bacteria.