| Literature DB >> 8212035 |
H B Hines1, S M Naseem, R W Wannemacher.
Abstract
Tritiated saxitoxinol was used to obtain preliminary information on saxitoxin metabolism in the rat. Sublethal doses of tritiated saxitoxinol (18.9-microCi/kg; 3.8 micrograms/kg) were injected i.v. into each of six rats. Urine and fecal samples were collected up to 144 hr post-injection. Within 4 hr, 60% of injected radioactivity was excreted in urine. No radioactivity was found in feces. High performance liquid chromatography analyses of urine showed that saxitoxinol was not metabolized by the rats.Entities:
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Year: 1993 PMID： 8212035 DOI： 10.1016/0041-0101(93)90226-9
Source DB: PubMed Journal: Toxicon ISSN： 0041-0101 Impact factor: 3.033