| Literature DB >> 8209202 |
P Meregalli1, M G Bianchetti, G Imoberdorf, J Lütschg, D Reymond, O H Oetliker.
Abstract
10 children (8 boys and 2 girls) with frequently relapsing idiopathic nephrotic syndrome were treated with levamisole (5 mg/kg weekly). In 6 children with steroid dependent nephrotic syndrome a marked reduction in steroids by 62% to 75% was possible. Severe, transient neutropenia was observed in one patient. Levamisole failed to influence the disease course positively in 3 patients with relapses associated with intercurrent illness. It is concluded that levamisole may favourably influence steroid dependence in children with frequently relapsing idiopathic nephrotic syndrome.Entities:
Mesh:
Substances:
Year: 1994 PMID: 8209202
Source DB: PubMed Journal: Schweiz Med Wochenschr ISSN: 0036-7672