Literature DB >> 8209202

[Levamisole in children with frequently recurring idiopathic nephrotic syndrome].

P Meregalli1, M G Bianchetti, G Imoberdorf, J Lütschg, D Reymond, O H Oetliker.   

Abstract

10 children (8 boys and 2 girls) with frequently relapsing idiopathic nephrotic syndrome were treated with levamisole (5 mg/kg weekly). In 6 children with steroid dependent nephrotic syndrome a marked reduction in steroids by 62% to 75% was possible. Severe, transient neutropenia was observed in one patient. Levamisole failed to influence the disease course positively in 3 patients with relapses associated with intercurrent illness. It is concluded that levamisole may favourably influence steroid dependence in children with frequently relapsing idiopathic nephrotic syndrome.

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Year:  1994        PMID: 8209202

Source DB:  PubMed          Journal:  Schweiz Med Wochenschr        ISSN: 0036-7672


  3 in total

1.  Population pharmacokinetics of levamisole in children with steroid-sensitive nephrotic syndrome.

Authors:  A R Kreeftmeijer-Vegter; T P C Dorlo; M P Gruppen; A de Boer; P J de Vries
Journal:  Br J Clin Pharmacol       Date:  2015-06-05       Impact factor: 4.335

2.  Experience with levamisole in frequently relapsing, steroid-dependent nephrotic syndrome.

Authors:  K Al-Saran; K Mirza; G Al-Ghanam; M Abdelkarim
Journal:  Pediatr Nephrol       Date:  2005-10-13       Impact factor: 3.714

Review 3.  Levamisole in steroid-sensitive nephrotic syndrome of childhood: the lost paradise?

Authors:  J C Davin; M P Merkus
Journal:  Pediatr Nephrol       Date:  2004-09-17       Impact factor: 3.714

  3 in total

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