Literature DB >> 8207671

Cetyl myristoleate isolated from Swiss albino mice: an apparent protective agent against adjuvant arthritis in rats.

H W Diehl1, E L May.   

Abstract

Cetyl myristoleate was isolated from National Institutes of Health, general purpose, Swiss albino mice that were immune to the polyarthritis induced in rats with Freund's adjuvant. This substance, or material synthesized from cetyl alcohol and myristoleic acid, afforded good protection against adjuvant-induced arthritic states in rats. In limited comparisons, cetyl oleate, also found in Swiss albino mice, gave lesser protection, whereas cetyl myristate and cetyl elaidate, the trans-isomer of cetyl oleate, appeared to be virtually ineffective. Dosage of the protective compound as well as the site of injection of Freund's adjuvant was important.

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Year:  1994        PMID: 8207671     DOI: 10.1002/jps.2600830307

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  8 in total

1.  In Vitro Effects of Cetylated Fatty Acids Mixture from Celadrin on Chondrogenesis and Inflammation with Impact on Osteoarthritis.

Authors:  Ariana Hudita; Bianca Galateanu; Sorina Dinescu; Marieta Costache; Anca Dinischiotu; Carolina Negrei; Miriana Stan; Aristidis Tsatsakis; Dragana Nikitovic; Dumitru Lupuliasa; Andra Balanescu
Journal:  Cartilage       Date:  2018-05-29       Impact factor: 4.634

2.  Association of cetylated fatty acid treatment with physical therapy improves athletic pubalgia symptoms in professional roller hockey players.

Authors:  Enrico Pampaloni; Elena Pera; Duilio Maggi; Riccardo Lucchinelli; Dante Chiappino; Andrea Costa; Veronica Venturini; Germano Tarantino
Journal:  Heliyon       Date:  2020-07-28

3.  Over the counter (OTC) oral remedies for arthritis and rheumatism: how effective are they?

Authors:  M W Whitehouse; M S Roberts; P M Brooks
Journal:  Inflammopharmacology       Date:  1999       Impact factor: 4.473

4.  Kre-Celazine(®) as a viable treatment for juvenile rheumatoid arthritis/juvenile idiopathic arthritis - a pilot study.

Authors:  Jeff Golini; Wendy Lou Jones
Journal:  J Med Food       Date:  2014-06-04       Impact factor: 2.786

5.  Concerning the anti-arthritic action of cetyl myristoleate in rats: an interim report.

Authors:  M W Whitehouse; R P McGeary
Journal:  Inflammopharmacology       Date:  1999       Impact factor: 5.093

6.  The minimal effective dose of cis-9-cetylmyristoleate (CMO) in persons presenting with knee joint pain: A double-blind, randomized, placebo-controlled trial.

Authors:  Sang Chul Lee; Hyun Seung Jin; Young Joo; Yong Chul Kim; Jee Youn Moon
Journal:  Medicine (Baltimore)       Date:  2017-03       Impact factor: 1.889

7.  A prospective observational study on the beneficial effects and tolerability of a cetylated fatty acids (CFA) complex in a patch formulation for shoulder tendon disorders.

Authors:  Rosaria Lanzisera; Alessandro Baroni; Gaetana Lenti; Elisabetta Geri
Journal:  BMC Musculoskelet Disord       Date:  2022-04-12       Impact factor: 2.362

8.  Non-NSAID over-the-counter (OTC) remedies for arthritis: good, bad or indifferent?

Authors:  M W Whitehouse; D E Butters
Journal:  Inflammopharmacology       Date:  1999       Impact factor: 5.093

  8 in total

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