Literature DB >> 8207153

Recurrent digoxin overdose and treatment with digoxin-specific Fab antibody fragments.

G M Bosse1, T M Pope.   

Abstract

A case of overdose with digoxin on three separate occasions is presented. The patient received digoxin-specific Fab antibody fragments on each presentation without adverse effects. A discussion of digoxin toxicity and specific treatment follows. Immunologic aspects of therapy are emphasized.

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Year:  1994        PMID： 8207153     DOI： 10.1016/0736-4679(94)90696-3

Source DB:  PubMed          Journal:  J Emerg Med        ISSN： 0736-4679            Impact factor:   1.484


  4 in total

Review 1.  Fab antibody fragments: some applications in clinical toxicology.

Authors:  Robert J Flanagan; Alison L Jones
Journal:  Drug Saf       Date:  2004       Impact factor: 5.606

2.  Suppression of antibody-mediated arthritis in mice by Fab fragments of the mediating antibodies.

Authors:  S Yoshino; M Sasahara; Pilaiwanwadee Hutamekalin; K Yamaki; N Mizutani; H Kuramoto
Journal:  Br J Pharmacol       Date:  2010-11       Impact factor: 8.739

Review 3.  Drugs and pharmaceuticals: management of intoxication and antidotes.

Authors:  Silas W Smith
Journal:  EXS       Date:  2010

4.  Drug overdoses requiring temporary cardiac pacing; a study of six cases treated at Altnagelvin Hospital, Londonderry.

Authors:  P G McGlinchey; A J McNeill
Journal:  Ulster Med J       Date:  1998-05
  4 in total

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