Literature DB >> 8206236

Two binding sites for naturally occurring inhibitors in mitochondrial and bacterial NADH:ubiquinone oxidoreductase (complex I).

T Friedrich1, T Ohnishi, E Forche, B Kunze, R Jansen, W Trowitzsch, G Höfle, H Reichenbach, H Weiss.   

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Year:  1994        PMID： 8206236     DOI： 10.1042/bst0220226

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


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  7 in total

1.  Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity.

Authors:  Aracely Garcia-Garcia; Annandurai Anandhan; Michaela Burns; Han Chen; You Zhou; Rodrigo Franco
Journal:  Toxicol Sci       Date:  2013-08-31       Impact factor: 4.849

2.  Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species.

Authors:  Romana Fato; Christian Bergamini; Marco Bortolus; Anna Lisa Maniero; Serena Leoni; Tomoko Ohnishi; Giorgio Lenaz
Journal:  Biochim Biophys Acta       Date:  2008-11-14

3.  Characterization and Discovery of a Selective Small-Molecule Modulator of Mitochondrial Complex I Targeting a Unique Binding Site.

Authors:  Jakob C Green; Yuqi Jiang; Liu He; Yiming Xu; Dong Sun; Timothy Keoprasert; Christopher Nelson; Unsong Oh; Edward J Lesnefsky; Glen E Kellogg; Qun Chen; Shijun Zhang
Journal:  J Med Chem       Date:  2020-10-02       Impact factor: 7.446

4.  The conformational changes induced by ubiquinone binding in the Na+-pumping NADH:ubiquinone oxidoreductase (Na+-NQR) are kinetically controlled by conserved glycines 140 and 141 of the NqrB subunit.

Authors:  Madeleine Strickland; Oscar Juárez; Yashvin Neehaul; Darcie A Cook; Blanca Barquera; Petra Hellwig
Journal:  J Biol Chem       Date:  2014-07-08       Impact factor: 5.157

5.  Detecting dopaminergic neuronal degeneration using diffusion tensor imaging in a rotenone-induced rat model of Parkinson's disease: fractional anisotropy and mean diffusivity values.

Authors:  Lan-Xiang Liu; Dan Du; Tao Zheng; Yuan Fang; Yan-Sheng Chen; Hui-Ling Yi; Qing-Yuan He; Da-Wei Gao; Qing-Lei Shi
Journal:  Neural Regen Res       Date:  2017-09       Impact factor: 5.135

6.  Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues.

Authors:  Xu-Wen Li; Jennifer Herrmann; Yi Zang; Philippe Grellier; Soizic Prado; Rolf Müller; Bastien Nay
Journal:  Beilstein J Org Chem       Date:  2013-07-31       Impact factor: 2.883

7.  Biosynthetic Plasticity Enables Production of Fluorinated Aurachins.

Authors:  Angela Sester; Katrin Stüer-Patowsky; Wolf Hiller; Florian Kloss; Stephan Lütz; Markus Nett
Journal:  Chembiochem       Date:  2020-05-05       Impact factor: 3.164
  7 in total

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